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1 Francis I Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California School of Medicine, San Francisco, Calif.
Heat-produced necrotizing lesions of the chick embryo pigment epithelium and retina are repaired by regeneration in these tissues. Regeneration is usually incomplete and may be disorderly. Quantitative effects are technically difficult, but eyes of 4 to 5 days' incubation seem more capable of recovery than those injured after 7 days of incubation. Regeneration of pigment epithelium precedes regeneration in the retina, and this suggests a trophic influence. Microphthahnia results more frequently when the anterior rim of the optic cup is insulted.
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