IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

(Investigative Ophthalmology and Visual Science. 1962;1:474-479.)
© 1962 by The Association for Research in Vision and Ophthalmology, Inc.

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by KUPFER, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by KUPFER, C.

Studies of Intraocular Pressure

II. The Histopathology of Experimentally Increased Intraocular Pressure in the Rabbit

CARL KUPFER 1

1 Howe Laboratory of Ophthalmology, Harvard University Medical School and the Massachusetts Eye and Ear Infirmary Boston, Mass.

The aqueous humor outflow channels of the rabbit eye were obstructed by placement of polyethylene tubing in the angle of the anterior chamber. Within 24 hours the intraocular pressure was elevated and remained so for 3 months after which time the animals were killed. Histologic examination verified the selective loss of ganglion cells, loss of myelin from optic nerve fibers, and deep excavation of the optic nerve. It is concluded that experimentally increased intraocular pressure can cause retinal and optic nerve changes in the rabbit eye which duplicate the pathologic changes of the retina associated with elevated intraocular pressure in man.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1962 by the Association for Research in Vision and Ophthalmology