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(Investigative Ophthalmology and Visual Science. 1962;1:728-744.)
© 1962 by The Association for Research in Vision and Ophthalmology, Inc.

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Retinoblastoma

A Study of two Cases by Electron Microscopy

RAYMOND A. ALLEN 1, HARRISON LATTA 1, and BRADLEY R. STRAATSMA 1

1 Department of Pathology and the Division of Ophthalmology, Department of Surgery, University of California Medical Center, Los Angeles, Calif.

The ultrastructure of two retinoblastomas includes cytologic features which are characteristic of neoplasia. Unusual degenerative changes were observed in both tumors. Rosettes were present in one case, and the cells which formed them showed some characteristics of ependyma of the primitive neural tube, and also of developing vision receptor cells. Structures resembling pericentriolar bodies were associated with basal bodies of cilia in rosettes.






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