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(Investigative Ophthalmology and Visual Science. 1971;10:733-744.)
© 1971 by The Association for Research in Vision and Ophthalmology, Inc.

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Development of the Rat Iris

MASATOSHI IMAIZUMI 1 and TOICHIRO KUWABARA 1

1 Howe Laboratory of Ophthalmology, Harvard University Medical School, and Massachusetts Eye and Ear Infirmary, Boston, Mass.

Development of the rat iris was studied electron microscopically. Development of the rat iris began on the sixteenth prenatal day and differentiated actively during the three days before birth. The iris showed mature structure by the end of the postnatal second week. The sequence of the smooth muscle formation from the neuroepithelial cell was specifically described. The differentiation began with formation of the basal infoldings. Myofilaments were found in the celh which had formed a bazement membrane around the infolded bazal and lateral cell membranes.

Key Words: rat iris • smooth muscle formation • basal infoldings • myofilaments • lateral cell membranes

Submitted on July 26, 1971
Accepted on August 11, 1971




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