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(Investigative Ophthalmology and Visual Science. 1971;10:911-919.)
© 1971 by The Association for Research in Vision and Ophthalmology, Inc.

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Comparative Study of Argon and Ruby Retinal Damage Thresholds

GEORG D. FRISCH 1, EDWIN S. BEATRICE 2, and ROBERT C. HOLSEN 2

1 Joint AMRDC-AMC Laser Safety Team, Frankford Arsenal Philadelphia, Pa.
2 Joint AMRDC-AMC Laser Safety Team, Frankford Arsenal, Philadelphia, Pa.

The eyes of rhesus monkeys were exposed to argon (514.5 nm.) and ruby (694.3 nm.) laser radiation. Data were obtained using 2.3 to 3 mm. and 7.5 to 8 mm. corneal spot diameters. Retinal exposure sites were examined by ophthalmoscopic and histopathologic techniques. Macular and extramacular exposure sites were separated and analyzed. Probit analysis was utilized in the evaluation of all data and regression lines, and associated confidence intervals were obtained. Utilization of flat preparations of the pigment epithelium and sensory layers of the retina confirmed damage at the lower power levels. Comparable lesions (in terms of ED50 points) were analyzed for the two systems to establish similarities and significant differences.

Key Words: comparative damage • ruby laser • argon laser • retinal pigment epithelium • rhesus monkey • probit analysis

Submitted on May 27, 1971
Accepted on September 14, 1971




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D. O. Adams, E. S. Beatrice, and R. B. Bedell
Retina: Ultrastructural Alterations Produced by Extremely Low Levels of Coherent Radiation
Science, July 7, 1972; 177(4043): 58 - 60.
[Abstract] [PDF]


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