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(Investigative Ophthalmology and Visual Science. 1971;10:144-146.)
© 1971 by The Association for Research in Vision and Ophthalmology, Inc.

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Corneal Exposure

Sodium Concentration in Aqueous and Lens Changes

LLOYD J. BRANSON 1 and MOSHE LAZAR 1

1 Department of Ophthalmology, Mount Sinai School of Medicine, City University of New York, New York, N. Y.

Reversible corneal exposure cataracts have been observed in many rodents. The postulated mechanism has been one of transcorneal evaporation of water increasing the concentration of the aqueous and osmotically affecting the lens. In this experiment, changes in the colligative properties of hamster aqueous were measured as related to corneal exposure and the development of lens opacity. A rise of sodium concentration of aqueous was found to parallel the appearance and progression of lens opacity.

Note:

This paper was read before the National meeting of the Association for Research in Vision and Ophthalmology, May 3, 1970.

Dr. Lazar is on leave from Ichilov Hospital, Tel-Aviv Medical School, Israel.

Key Words: exposure cataract • aqueous concentration • sodium ion • colligative properties • reversible opacity

Submitted on December 2, 1970
Accepted on December 18, 1970






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