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(Investigative Ophthalmology and Visual Science. 1971;10:89-99.)
© 1971 by The Association for Research in Vision and Ophthalmology, Inc.

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Electron Microscopic Study of Hereditary Corneal Edema

ATSUSHI KANAI 1, STEPHEN WALTMAN 1, FRANK M. POLACK 1, and HERBERT E. KAUFMAN 2

1 Department of Ophthalmology, College of Medicine, University of Florida and the Veterans Administration Hospital, Gainesville, Fla.
2 Department of Ophthalmology, College of Medicine, University of Florida and the Veterans Administration Hospital Gainesville, Fla.

Hereditary corneal edema is a previously undescribed corneal dystrophy thought to be transmitted as a dominant trait. This study presents five members of a family with hereditary corneal edema and describes the uniqueness of their condition from other corneal dystrophies. Emphasis is placed on electron microscopic studies of a corneal button from one member who had penetrating keratoplasty.

Key Words: heredity • corneal dystrophy • corneal edema • collagen fibrils • Descemet's membrane • corneal endothelium • histopathology • light microscopy • electron microscopy

Submitted on October 19, 1970
Accepted on December 28, 1970






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