IOVS British Journal of Pharmacology
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(Investigative Ophthalmology and Visual Science. 1971;10:625-636.)
© 1971 by The Association for Research in Vision and Ophthalmology, Inc.

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Photopic Abnormalities in Congenital Stationary Nightblindness

ALEX E. KRILL 1 and DEIDRE MARTIN 1

1 Eye Research Laboratories, the University of Chicago, Chicago, Ill.

Fourteen patients with congenital nightblindness, representing all three hereditary types, were studied, and all were found to have some type of photopic abnormality. The photopic abnormalities consisted of abnormal visual acuity, slower-than-normal final cone thresholds, elevated cone thresholds, subnormal photopic responses, slower-than-normal photopic a- and b-wave implicit times, and low flicker fusion frequencies. One or more of these abnormalities were noted in all patients. Only visual acuity could be related to the specific type of inheritance involved. No other photopic or scotopic abnormality bore a constant relation to the hereditary pattern. Congenital nightblindness, regardless of the hereditary type, is characterized by both scotopic and photopic abnormalities.

Key Words: congenital nightblindness • photopic abnormalities • scotopic abnormalities • visual acuity • cone threshold • flicker fusion frequency • a- and b-wave implicit times

Submitted on May 18, 1971
Accepted on July 2, 1971




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