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1 Neuro-Ophthalmology Unit, Departments of Neurological Surgery, Neurology, and Ophthalmology, University of California, San Francisco
2 Neuro-Ophthalmology Unit, Departments of Neurological Surgery, Neurology, and Ophthalmology, University of California, San Francisco; Department of Ophthalmology, University of Göteborg, Sweden
3 Neuro-Ophthalmology Unit, Departments of Neurological Surgery, Neurology, and Ophthalmology, University of California, San Francisco; Department of Ophthalmology, Pacific Medical Center, San Francisco
Early attrition of nerve fiber bundles in glaucoma causes slit-like gaps to appear among the normally uniform, striated arcuate bundles of the retinal nerve fiber layer. The nerve fiber layer thins progressively, and its vessels become exposed as the defects coalesce, deepen, and widen with advancing disease. These changes in the peripapillary retina are exemplified photographically and compared with perimetric findings. We believe that these fundoscopic signs provide the earliest objective evidence of nerve fiber wasting in eyes with chronically elevated intraocular pressure.
Key Words: glaucoma • intraocular hypertension • retina • retinal nerve fiber layer • optic disc • examination techniques • ophthalmoscopy • fundus photography
Submitted on June 5, 1973
Accepted on June 7, 1973
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