IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

(Investigative Ophthalmology and Visual Science. 1973;12:491-496.)
© 1973 by The Association for Research in Vision and Ophthalmology, Inc.

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ARMALY, M. F.
Right arrow Articles by RAO, K. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ARMALY, M. F.
Right arrow Articles by RAO, K. R.

The Effect of Pilocarpine Ocusert With Different Release Rates on Ocular Pressure

MANSOUR F. ARMALY 1 and K. R. RAO 1

1 Department of Ophthalmology, The George Washington University Medical Center, Washington, D. C. 20037

The pilocarpine-Ocusert system exhibits a dose-effect relationship such that a greater release rate results in a greater ocular hypotensive effect; the effect is not appreciably modified when release rates are in excess of 50 µg per hour. The magnitude of the mean per cent reduction in outflow pressure with 50 µg per hour is comparable to that reported for pilocarpine concentrations of 4 to 8 per cent. The hypotensive effect of Ocusert-50 is significantly greater than that of pilocarpine 2 per cent ophthalmic solution. Clinically, a single Ocusert unit can maintain controlled ocular pressure level in the sensitive individual for 2 to 4 days, and this control seems to increase with the release rate.

Submitted on May 15, 1973
Accepted on May 16, 1973




This article has been cited by other articles:


Home page
 NEJMHome page
W. L.M. Alward
Medical Management of Glaucoma
N. Engl. J. Med., October 29, 1998; 339(18): 1298 - 1307.
[Full Text] [PDF]

Home page
 Journal of Bioactive and Compatible PolymersHome page
S. Dumitriu, M. Popa, P. Vancea, and D. Costin
Polycomponent Ophthalmic Inserts with Polysaccharide Support
Journal of Bioactive and Compatible Polymers, January 1, 1988; 3(4): 370 - 389.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the Association for Research in Vision and Ophthalmology