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(Investigative Ophthalmology and Visual Science. 1974;13:308-310.)
© 1974 by The Association for Research in Vision and Ophthalmology, Inc.

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Effects of Fasting and Refeeding on Morphological and Biochemical Properties of the Porcine Lens

Y. LEE 1, R. G. KAUFFMAN 2, and G. DEVENECIA 3

1 Campbell Soup Co., Camden, N. J. 08101
2 Muscle Biology Laboratory and Department of Meat and Animal Science
3 Department of Ophthalmology, University of Wisconsin Medical Center

Severe starvation caused minor morphologic changes in porcine eye lenses, fine punctate opacities in cortex, a few water vacuoles, and enlarged, prominent Y sutures. However, these abnormalities disappeared upon rehabilitation. The sedimentation analyses of porcine lens soluble proteins exhibited three components with values for S°20, of 18.2, 9.0, and 2.7 S. The relative distribution of these components were 21, 38, and 41 per cent for 18.2, 9.0, and 2.7 S components, respectively. The sedimentation patterns and the distribution of three protein components were not affected by severe starvation.

Key Words: lens • fasting • nutrition • proteins • porcine

Submitted on April 27, 1973






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