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(Investigative Ophthalmology and Visual Science. 1974;13:455-457.)
© 1974 by The Association for Research in Vision and Ophthalmology, Inc.

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Reports: Experimental Glaucoma in the Rhesus Monkey

DOUGLAS GAASTERLAND 1 and CARL KUPFER 1

1 Clinical Branch, National Eye Institute, National Institutes of Health, Department of Health, Education, and Welfare, Bethesda, Md. 20014

Repeated, circumferential argon laser photocoagulation of the trabecular meshwork area of the anterior chamber angle of normal Rhesus monkeys causes a sustained elevation of the intraocular pressure and marked reduction of the outflow facility. During the observation period of this study, cupping of the optic nervehead developed. Preliminary histopathologic examination revealed localized scarring of the anterior chamber angle structures. Retinal and optic nerve changes, similar to those seen in human chronic, open-angle glaucoma, were seen. The method to produce this experimental glaucoma is reported.

Key Words: experimental glaucoma • Rhesus monkey • perfusion • argon laser

Submitted on March 21, 1974




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