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(Investigative Ophthalmology and Visual Science. 1974;13:623-626.)
© 1974 by The Association for Research in Vision and Ophthalmology, Inc.

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Epithelial Cell Phagocytosis of Listeria Monocytogenes in the Conjunctiva

MATTHEW C. ZIMIANSKI 1, CHANDLER R. DAWSON 1, and BIRGITTA TOGNI 1

1 Francis I. Proctor Foundation for Research in Ophthalmology and the Departments of Ophthalmology and Microbiology, University of California, San Francisco.

Guinea pig conjunctivas inoculated with Listeria monocytogenes were studied by light microscopy and transmission electron microscopy. The epithelial cell of the conjunctiva was found to phagocytose L. monocytogenes as early as 15 minutes after inocidation, long before the appearance of polymorphonuclear cells. The epithelial cells of the mucous membranes appear to participate actively in the host response to this pathogenic organism.

Key Words: conjunctiva • conjunctivitis • Listeria monocytogenes • phagocytosis

Submitted on February 5, 1974






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