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(Investigative Ophthalmology and Visual Science. 1974;13:695-697.)
© 1974 by The Association for Research in Vision and Ophthalmology, Inc.

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Antinuclear Antibodies in Open-Angle Glaucoma

STEPHEN R. WALTMAN 1 and DAVID YARIAN 1

1 Department of Ophthalmology, Washington University School of Medicine, 660 So. Euclid Ave., St. Louis, Mo. 63110

Positive antinuclear antibody (ANA) reactions were found in 44 per cent of patients with openangle glaucoma. The age or sex of the patients did not affect the results. This was highly significant when compared to the 7.5 per cent positive reactions in the control population. Patients with a high response to topical corticosteroids hail a 7 per cent positive reaction rate which was not significantly different from the control subjects. This is another piece of information indicating a possible disturbance of immunologic function in glaucoma patients.

Key Words: glaucoma • autoantibodies • antinuclear antibodies

Submitted on December 7, 1973






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