IOVS Infection and Immunity
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Investigative Ophthalmology & Visual Science, Vol 14, 762-763, Copyright © 1975 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Ara-A and IDU therapy of human superficial herpetic keratitis

PR Laibson, R Hyndiuk, JH Krachmer and RO Schultz

Ara-A ointment was compared to IDU ointment in patients with dendritic herpes simplex virus infection of the corneal epithelium. Twenty-eight patients were treated with Ara-A ointment and twenty-four with IDU ointment. The lesions healed in 5.1 days with Ara-A and in 6.9 days with IDU. This drug was given in a double-controlled manner, so that neither the patient, nor the investigator knew which drug the patient was receiving. The patient groups were comparable as to length of the dendritic lesion and duration of symptoms. The adverse reactions to each of these drugs were comparable and in no case was there any permanent ocular change from drug use.




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Copyright © 1975 by the Association for Research in Vision and Ophthalmology