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Investigative Ophthalmology & Visual Science, Vol 14, 114-124, Copyright © 1975 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Effects of monosodium glutamate on chick embryo retina in culture

L Reif-Lehrer, J Bergenthal and L Hanninen

Monosodium glutamate added to 12-day chick embryo retinas in culture causes severe morphologic damage to the retina as judged by light microscopic examination. Damage is evident after a few hours with concentrations as low as 0.3 mM. Glutamyltransferase induction is also appreciably inhibited by the amino acid. General protein synthesis and RNA synthesis appear to be less affected.




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Copyright © 1975 by the Association for Research in Vision and Ophthalmology