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Investigative Ophthalmology & Visual Science, Vol 23, 528-530, Copyright © 1982 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Adrenergic influence on iris stromal pigmentation: evidence for alpha- adrenergic receptors

L Odin and FE O'Donnell Jr

Adrenergic influence on iris pigmentation in newborn pigmented rabbits was studied. Selective adrenergic antagonists were used topically to determine whether they could inhibit iris pigmentation. Unilateral, topical administration of an alpha-adrenergic antagonist (thymoxamine hydrochloride 1/2%) was not associated with iris hypochromia. Adrenergic influence on iris stromal melanogenesis appears to be mediated by alpha-adrenergic receptors.


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 Arch OphthalmolHome page
G.-L. Zhan, C. B. Toris, C. B. Camras, Y.-L. Wang, and L. Z. Bito
Prostaglandin-Induced Iris Color Darkening: An Experimental Model
Arch Ophthalmol, August 1, 1998; 116(8): 1065 - 1068.
[Abstract] [Full Text] [PDF]


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Copyright © 1982 by the Association for Research in Vision and Ophthalmology