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Investigative Ophthalmology & Visual Science, Vol 24, 128-133, Copyright © 1983 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Ethambutol changes the color coding of carp retinal ganglion cells reversibly

BW van Dijk and H Spekreijse

The influence of ethambutol on retinal function was studied by recording ganglion cell responses in isolated carp retinas superfused with a Ringer solution containing different concentrations of ethambutol (0 mg/liter, 10 mg/liter, 20 mg/liter, 30 mg/liter). The results indicate that ethambutol reversibly affects color opponency, without changing the sensitivity of the underlying receptor processes. The amacrine and bipolar cells are the most likely candidates to be affected by ethambutol.


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 Br. J. Ophthalmol.Home page
T Y Y Lai, W-M Chan, D S C Lam, and E Lim
Multifocal electroretinogram demonstrated macular toxicity associated with ethambutol related optic neuropathy
Br. J. Ophthalmol., June 1, 2005; 89(6): 774 - 775.
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