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Investigative Ophthalmology & Visual Science, Vol 24, 165-168, Copyright © 1983 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Acute effect of thymoxamine on aqueous humor formation in the epinephrine-treated normal eye as measured by fluorophotometry

DA Lee, RF Brubaker and S Nagataki

The acute effect of 0.5% thymoxamine and 1% epinephrine on aqueous humor flow was evaluated by fluorophotometry in 25 normal human subjects in a randomized, double-blind, placebo-controlled study. Changes in intraocular pressure, anterior chamber volume, and pupil diameter were also measured. The results of this study indicate that epinephrine alone increases aqueous humor flow by 19% and that thymoxamine in a dose sufficient to produce miosis does not alter this acute effect of epinephrine.




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Copyright © 1983 by the Association for Research in Vision and Ophthalmology