IOVS Read the Free BMJ
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mauger, T. F.
Right arrow Articles by Hill, R. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mauger, T. F.
Right arrow Articles by Hill, R. M.

Investigative Ophthalmology & Visual Science, Vol 24, 582-585, Copyright © 1983 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Aerobic responses of the cornea to alkali measured in vivo

TF Mauger and RM Hill

With the use of a micropolarographic system, the effects of a series of unbuffered sodium hydroxide concentrations on oxygen uptake by the corneal epithelium of rabbit were measured in vivo. Based on an exposure model of 10 sec. followed by a saline rinse, concentrations of greater than 0.10 N were found to cause an abrupt and severe decline in oxygen uptake, with oxygen flux responses associated with 0.13 N and greater being indistinguishable 10 min later from those of a cornea completely denuded of epithelium. Initial flux variations, characteristic of exposure responses to concentrations of 0.10 N or less, gradually diminished, however, stabilizing within 1 hr to levels not significantly different (P less than 0.01) from pre-exposure fluxes or those of saline controls.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1983 by the Association for Research in Vision and Ophthalmology