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Investigative Ophthalmology & Visual Science, Vol 25, 112-115, Copyright © 1984 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Characterization of somatostatin-like immunoreactivity in vertebrate retinas

D Marshak and T Yamada

Large differences in retinal concentration of somatostatin-like immunoreactivity (SLI) were observed even among closely related species. Hog and chicken retinas, like those of goldfish and frog described previously, contained roughly equal amounts of SLI coeluting with somatostatin tetradecapeptide (S14) and octacosapeptide (S28) on Sephadex G 50 chromatography. In contrast, virtually all of the SLI from rat retina coeluted with S14, and nearly all of the bovine retinal SLI coeluted with S28. These species differences may reflect differences in post-translational processing of the various molecular forms of retinal SLI.




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Copyright © 1984 by the Association for Research in Vision and Ophthalmology