IOVS Human Reproduction
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Investigative Ophthalmology & Visual Science, Vol 25, 217-218, Copyright © 1984 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Imipramine inhibiton of ragweed allergic conjunctivitis

J Sugar, M Nyberg, J Bernstein, A Barlow and W Slater

Twenty-seven patients sensitive to ragweed pollen were treated with topical imipramine 0.05% in one eye and vehicle in the other in a double-masked fashion. The eyes treated with imipramine showed significantly less redness, tearing, and discomfort after exposure to pollen extract. Imipramine, a tricyclic antidepressant, appears to be an effective antihistamine in the eye.




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Copyright © 1984 by the Association for Research in Vision and Ophthalmology