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Investigative Ophthalmology & Visual Science, Vol 25, 801-809, Copyright © 1984 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Natural history of experimental histoplasmic choroiditis in the primate. I. Clinical features

RE Smith, S Dunn and JV Jester

The clinical features of the long-term (3-year) natural history of experimental histoplasmic choroiditis in primates are documented in this report. The acute choroiditis resolved into four types of lesions: chorioretinal adhesions (atrophic scars) (2%); retinal pigment epithelial window defects (21%); subclinical lesions (19%); and "disappearing" lesions (58%). It was noted that the most obvious, acute lesions tend to disappear by clinical examination with long-term follow up. No subretinal neovascularization or spontaneous "reactivation" was observed.


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