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Investigative Ophthalmology & Visual Science, Vol 25, 843-850, Copyright © 1984 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Morphology of hydrogel implants used for refractive keratoplasty

JR Samples, PS Binder, EY Zavala, SD Baumgartner and JK Deg

The pathology of 14 keratophakia procedures in nine nonhuman primates using various hydrogel lenses as donor lenticles is presented. The lenses were treated as if they were human donor corneas using currently practiced keratophakia procedures. This included microkeratome resection of the recipient cornea, staining of the lenses before cryolathing and, in most instances, lathing according to a modified computer program after which the lenses were inserted into the previously dissected recipient lamellar bed. There was no histologic evidence of an inflammatory reaction to the hydrogels. The major pathologic feature was the presence of activated keratocytes lining the dissected intrastromal pockets.




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Copyright © 1984 by the Association for Research in Vision and Ophthalmology