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Investigative Ophthalmology & Visual Science, Vol 25, 864-867, Copyright © 1984 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

The response range of the blue-cone pathways: a source of vulnerability to disease

DC Hood, NI Benimoff and VC Greenstein

Retinal disease preferentially affects the sensitivity of the "blue"- cone pathways. This vulnerability to disease may be due, in part, to a more limited response range. A psychophysical technique, the probe- flash paradigm, was used to test this hypothesis. The data suggest that the S-cone pathways have a more limited response range than the L-cone pathways. Explanations for blue-cone vulnerability are discessed in the context of this finding.


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