IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ishibashi, T.
Right arrow Articles by Tanaka, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ishibashi, T.
Right arrow Articles by Tanaka, K.

Investigative Ophthalmology & Visual Science, Vol 26, 125-127, Copyright © 1985 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Fibrinolytic activity of the retinae in streptozotocin-diabetic rats

T Ishibashi, S Inoue and K Tanaka

Fibrinolytic activity of the retinae in control and diabetic rats was assayed quantitatively in twenty male rats made diabetic by giving a single injection of streptozotocin. All these rats were killed at either 3 months or 12 months. Ten saline-injected rats and five rats treated with 3-0-methylglucose and streptozotocin served as controls. As the plasminogen activator activity in diabetic rats maintained for 12 months was significantly lower than that in controls, we postulate that there may be a poor defense mechanism against microthrombus formation in the retinal vasculature of diabetics, which may contribute to the development of diabetic retinopathy.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1985 by the Association for Research in Vision and Ophthalmology