IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bachman, W. G.
Right arrow Articles by Wilson, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bachman, W. G.
Right arrow Articles by Wilson, G.

Investigative Ophthalmology & Visual Science, Vol 26, 1484-1488, Copyright © 1985 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Essential ions for maintenance of the corneal epithelial surface

WG Bachman and G Wilson

It is generally believed that tears are required to furnish only oxygen to the corneal epithelium. However, as tears are a very complicated solution, it is likely that other factors are essential to the cells of the corneal surface. The amount of light scattered from the epithelial surface of the excised rabbit cornea was examined with the in vitro specular microscope while the epithelium was bathed in different solutions. It was shown that the epithelial surface was maintained best with a buffered solution containing potassium, calcium, magnesium, phosphate and bicarbonate, in addition to sodium chloride. The solution was named Basic Tear Solution (BTS). The effect was not due to osmolarity. Potassium was particularly important, as corneas bathed with sodium chloride and potassium chloride were maintained better than corneas bathed with sodium chloride only. The appearance of the epithelial surface was different in these bathing solutions. In sodium chloride the surface scattered more light and more cells were sloughed. Least light was scattered in BTS, and cell-sloughing was at a minimum. Thus, the rate at which cells were sloughed from the epithelial surface and the quality of the surface were dependent on the bathing solution.


This article has been cited by other articles:


Home page
 IOVSHome page
J. L. Ubels, H. M. Hoffman, S. Srikanth, J. H. Resau, and C. P. Webb
Gene Expression in Rat Lacrimal Gland Duct Cells Collected Using Laser Capture Microdissection: Evidence for K+ Secretion by Duct Cells
Invest. Ophthalmol. Vis. Sci., May 1, 2006; 47(5): 1876 - 1885.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1985 by the Association for Research in Vision and Ophthalmology