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Investigative Ophthalmology & Visual Science, Vol 26, 1740-1744, Copyright © 1985 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Selective binding affinity of human plasma fibronectin for the collagens I-IV

DM Worthen, PH Cleveland, JR Slight and J Abare

The binding of plasma fibronectin to the collagens I, II, and III was greater in a cohort of glaucoma patients. In contrast, binding of plasma fibronectin to collagen type IV was less in 39 glaucoma patients than in any of 3 other diagnostic categories, including 92 patients that were normal, cataract, and glaucoma suspect patients. This observation may have significance in further understanding the control of aqueous outflow resistance in glaucoma and nonglaucoma patients.




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Copyright © 1985 by the Association for Research in Vision and Ophthalmology