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Investigative Ophthalmology & Visual Science, Vol 26, 384-388, Copyright © 1985 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

DNA repair synthesis in the rat retina following in vivo exposure to 300-nm radiation

LM Rapp, JG Jose and DG Pitts

Quantitative autoradiography was used to study the incorporation of 3H- thymidine into the retina of albino rats following in vivo exposure to 300-nm radiation. Relative to background labeling in unexposed eyes, there was 8-20 times as much label per unit area in the outer nuclear layer, inner nuclear layer, and ganglion cells of 300-nm exposed retinas. The photoreceptor inner segments also showed thymidine labeling in both control and exposed retinas.


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V. T. Ciavatta, S. A. Padove, J. H. Boatright, and J. M. Nickerson
Mouse Retina Has Oligonucleotide-Induced Gene Repair Activity
Invest. Ophthalmol. Vis. Sci., July 1, 2005; 46(7): 2291 - 2299.
[Abstract] [Full Text] [PDF]


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