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Investigative Ophthalmology & Visual Science, Vol 26, 789-796, Copyright © 1985 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Neodymium:YAG laser iridotomy in the cynomolgus monkey

DM Dragon, AL Robin, IP Pollack, HA Quigley, WR Green, TG Murray, ML Hotchkiss and S D'Anna

The histologic effects of various Neodymium:YAG laser energy levels were evaluated after iridotomy formation in cynomolgus monkey eyes. Scanning election microscopy of the corneal endothelium above the treated areas revealed no significant cell loss or pleomorphism when compared to the adjacent untreated areas. Light and phase contrast microscopy demonstrated closure of the iridotomies in most cases by a bridge of iris pigment epithelium. In several specimens, stromal tissue and pigment laden cells were present over the attenuated iris pigment epithelium. There were four lens opacities with rupture of the anterior lens capsule and anterior epithelial cell hyperplasia in one. No damage was apparent in the trabecular meshwork or retina with light microscopy or fluorescein angiography.




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Copyright © 1985 by the Association for Research in Vision and Ophthalmology