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Investigative Ophthalmology & Visual Science, Vol 26, 1182-1185, Copyright © 1985 by Association for Research in Vision and Ophthalmology
ARTICLES AND REPORTS |
M del Cerro, DM Gash, GN Rao, MF Notter, SJ Wiegand and M Gupta
Embryonic rat retinae transplanted into the anterior chamber of adult rat eyes of the same or different strain survive and grow. Light and electron microscopic studies show that the transplants undergo histogenetic differentiation, resulting in the development of mature inner and outer layer neurons and Muller glial cells. Vascular connections develop between the host iris and the retinal transplant. These initial observations indicate that retinal transplantation to a recipient eye is a procedure which offers ample opportunities for the study of problems related to neural development, retinal plasticity and repair.
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