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Investigative Ophthalmology & Visual Science, Vol 26, 1303-1305, Copyright © 1985 by Association for Research in Vision and Ophthalmology
ARTICLES AND REPORTS |
NA Rao and GE Marak Jr
An experimental granulomatous uveitis in the Brown Norway rat is characterized by large numbers of giant cells and epithelioid cells containing uveal pigment. Ultrastructurally, the epithelioid cells and the giant cells exhibited melanosomes and individual melanin granules in the absence of phagocytic membranes and compound pigment granules. These observations support the view that the pigment containing giant cells may develop from uveal melanocytes.
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