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Investigative Ophthalmology & Visual Science, Vol 27, 103-107, Copyright © 1986 by Association for Research in Vision and Ophthalmology


ARTICLES AND REPORTS

H2O2-modification of Na,K-ATPase. Alterations in external Na+ and K+ stimulation of K+ influx

MH Garner, WH Garner and A Spector

Studies, at steady state, of the Na,K-ATPase dependent influx of K+ into bovine lenses in organ culture are used to characterize further the H2O2-modification of the Na+ pump. Control lenses display constants for interaction with external Na+ and K+ similar to those obtained for the erythrocyte. H2O2 treatment of the bovine lens leads to total loss of external Na+ stimulation and alteration of external K+ stimulation.


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