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Investigative Ophthalmology & Visual Science, Vol 27, 92-97, Copyright © 1986 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

The flow of aqueous humor through micro-porous filters

M Johnson, CR Ethier, RD Kamm, WM Grant, DL Epstein and D Gaasterland

Flow resistance was measured as bovine and primate aqueous humor was passed through Nuclepore polycarbonate filters having flow dimensions similar to those found within the juxtacanalicular meshwork of the aqueous outflow network. The results indicate that aqueous humor has a greater flow resistance than isotonic saline; this greater resistance is attributable to proteins or glycoproteins in aqueous humor that obstruct the filters. If the same phenomenon is operative in the aqueous outflow network, it would help to explain discrepancies between calculated and measured aqueous outflow resistance.


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A. Goldwich, C. R. Ethier, D. W.-H. Chan, and E. R. Tamm
Perfusion with the Olfactomedin Domain of Myocilin Does Not Affect Outflow Facility
Invest. Ophthalmol. Vis. Sci., May 1, 2003; 44(5): 1953 - 1961.
[Abstract] [Full Text] [PDF]

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P. Russell, E. R. Tamm, F. J. Grehn, G. Picht, and M. Johnson
The Presence and Properties of Myocilin in the Aqueous Humor
Invest. Ophthalmol. Vis. Sci., April 1, 2001; 42(5): 983 - 986.
[Abstract] [Full Text]


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