Investigative Ophthalmology & Visual Science, Vol 27, 1560-1563, Copyright © 1986 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Mechanisms of subretinal fluid resorption in the cat eye

A Negi and MF Marmor

Small, non-rhegmatogenous retinal detachments (blebs) were made in cat eyes by injecting fluid into the subretinal space, and the time course of fluid resorption was monitored. Blebs made with Hanks' solution over the pigmented RPE resorbed 22% faster than those over the tapetum. Blebs made with a non-ionic solution (isotonic sucrose) took 43% longer to resorb than those made with Hanks' solution, and blebs containing 3 X 10(-3) M sodium cyanide took 32% longer than controls. These results suggest that active ionic transport is involved in the absorption of subretinal fluid in the cat, as it is in the rabbit. Oncotic pressure in the choroid may also contribute to resorption, because blebs made with autologous serum took roughly 3 times longer to resorb than those made with non-proteinaceous Hanks' solution. The retinal vascular system does not appear to contribute, since the resorption time was similar for Hanks' blebs made under normal retina and those made under ischemic retina (produced by occluding retinal branch arteries with argon laser photocoagulation or endodiathermy).

This article has been cited by other articles:

				A M Joussen, P Walter, C P Jonescu-Cuypers, K Koizumi, V Poulaki, K U Bartz-Schmidt, G K Krieglstein, and B Kirchhof Retinectomy for treatment of intractable glaucoma: long term results Br. J. Ophthalmol., September 1, 2003; 87(9): 1094 - 1102. [Abstract] [Full Text] [PDF]

				W. M. Peterson, C. Meggyesy, K. Yu, and S. S. Miller Extracellular ATP Activates Calcium Signaling, Ion, and Fluid Transport in Retinal Pigment Epithelium J. Neurosci., April 1, 1997; 17(7): 2324 - 2337. [Abstract] [Full Text] [PDF]