IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tsuboi, S.
Right arrow Articles by Pederson, J. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tsuboi, S.
Right arrow Articles by Pederson, J. E.

Investigative Ophthalmology & Visual Science, Vol 29, 1652-1655, Copyright © 1988 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Volume flow across the isolated retinal pigment epithelium of cynomolgus monkey eyes

S Tsuboi and JE Pederson
Department of Ophthalmology, University of Minnesota, Minneapolis.

The retinal pigment epithelium (RPE)-choroid was isolated from cynomolgus monkey eyes with experimental retinal detachments and the volume flow was determined in vitro using Ussing-type chambers. With zero pressure difference across the membrane, retina-to-choroid volume flow was 5.0 microliter/hr/cm2 in eyes with subacute retinal detachments (1-2 weeks). In eyes with chronic retinal detachment (8-20 months), the flow was 7.3 microliter/hr/cm2. Volume flow was not affected by the elimination of ambient bicarbonate. Transepithelial potential difference and resistance were 8.9 mV, retinal side positive, and 339 ohm-cm2, respectively, in chronic retinal detachments. It is concluded that there is a posteriorly directed flow of fluid across the RPE in cynomolgus monkey eyes with chronic retinal detachments.


This article has been cited by other articles:


Home page
 PhysiologyHome page
C. Hartzell, Z. Qu, I. Putzier, L. Artinian, L.-T. Chien, and Y. Cui
Looking Chloride Channels Straight in the Eye: Bestrophins, Lipofuscinosis, and Retinal Degeneration
Physiology, October 1, 2005; 20(5): 292 - 302.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
J. Hillenkamp, A. A. Hussain, T. L. Jackson, J. R. Cunningham, and J. Marshall
Taurine Uptake by Human Retinal Pigment Epithelium: Implications for the Transport of Small Solutes between the Choroid and the Outer Retina
Invest. Ophthalmol. Vis. Sci., December 1, 2004; 45(12): 4529 - 4534.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the Association for Research in Vision and Ophthalmology