| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 From the New England College of Optometry, Boston, Massachusetts; the 2 University of Alabama School of Optometry, Birmingham, Alabama; and the 3 University Medical Center, Stony Brook, New York.
PURPOSE. To describe baseline refractive and ocular component measures in children with myopia enrolled in the Correction of Myopia Evaluation Trial (COMET). COMET is a multicenter, randomized clinical trial to evaluate whether progressive-addition lenses slow the progression of juvenile-onset myopia compared with single-vision lenses.
METHODS. Four hundred sixty-nine children with myopia between -1.25 and -4.50 D spherical equivalent and without eye or systemic conditions known to affect refractive development were recruited from four geographically and ethnically diverse communities in the United States. Their ages were 6 to 11 years inclusive, and 52% were girls. The main outcome measure for the overall trial is progression of myopia determined by cycloplegic autorefraction after inducement of cycloplegia with 2 drops of 1% tropicamide. Axial length, the secondary outcome measure, was assessed by ultrasonography. The distance correction was determined by subjective methods before cycloplegia, with noncycloplegic autorefraction values as the starting point.
RESULTS. Because data were similar in both eyes, they are reported for the right eye only. The mean spherical equivalent measured by cycloplegic autorefraction was -2.38 ± 0.81 D. Young children had significantly less myopia than older children (P = 0.03), but the amount of myopia did not differ by gender or ethnicity. Mean axial dimensions were 4.0 ± 0.2 mm (anterior chamber), 3.4 ± 0.2 mm (lens), 16.8 ± 0.7 mm (vitreous chamber), and 24.1 ± 0.7 mm (axial length). Girls’ eyes had significantly shorter axial length than boys’ (P < 0.0001). Mean corneal radii were 7.73 ± 0.25 mm (horizontal) and 7.59 ± 0.24 mm (vertical). Ninety-five percent of the eyes had a ratio of axial length to corneal radius higher than 3.0.
CONCLUSIONS. These baseline measures provide cross-sectional data on a large group of ethnically diverse children with myopia. Refractive and axial component dimensions are consistent with data in other studies showing that myopic eyes have longer vitreous chambers than emmetropic eyes. The measures reported herein will serve as a basis for examining changes that occur over a minimum of 3 years of follow-up of children enrolled in COMET.
This article has been cited by other articles:
|
|
 |
|
  S. Hasebe, H. Ohtsuki, T. Nonaka, C. Nakatsuka, M. Miyata, I. Hamasaki, and S. Kimura Effect of Progressive Addition Lenses on Myopia Progression in Japanese Children: A Prospective, Randomized, Double-Masked, Crossover Trial Invest. Ophthalmol. Vis. Sci., July 1, 2008; 49(7): 2781 - 2789. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. H. Trivedi and M. E. Wilson Keratometry in Pediatric Eyes With Cataract Arch Ophthalmol, January 1, 2008; 126(1): 38 - 42. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. H. Trivedi and M. E. Wilson Biometry Data from Caucasian and African-American Cataractous Pediatric Eyes Invest. Ophthalmol. Vis. Sci., October 1, 2007; 48(10): 4671 - 4678. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Kurtz, L. Hyman, J. E. Gwiazda, R. Manny, L. M. Dong, Y. Wang, M. Scheiman, and the COMET Group Role of Parental Myopia in the Progression of Myopia and Its Interaction with Treatment in COMET Children Invest. Ophthalmol. Vis. Sci., February 1, 2007; 48(2): 562 - 570. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Ojaimi, K. A. Rose, I. G. Morgan, W. Smith, F. J. Martin, A. Kifley, D. Robaei, and P. Mitchell Distribution of Ocular Biometric Parameters and Refraction in a Population-Based Study of Australian Children Invest. Ophthalmol. Vis. Sci., August 1, 2005; 46(8): 2748 - 2754. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Hyman, J. Gwiazda, M. Hussein, T. T. Norton, Y. Wang, W. Marsh-Tootle, D. Everett, and for the COMET Study Group Relationship of Age, Sex, and Ethnicity With Myopia Progression and Axial Elongation in the Correction of Myopia Evaluation Trial Arch Ophthalmol, July 1, 2005; 123(7): 977 - 987. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Gwiazda, L. Hyman, T. T. Norton, M. E. M. Hussein, W. Marsh-Tootle, R. Manny, Y. Wang, and D. Everett Accommodation and Related Risk Factors Associated with Myopia Progression and Their Interaction with Treatment in COMET Children Invest. Ophthalmol. Vis. Sci., July 1, 2004; 45(7): 2143 - 2151. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. E. Manny, M. Hussein, J. Gwiazda, and W. Marsh-Tootle Repeatability of ETDRS Visual Acuity in Children Invest. Ophthalmol. Vis. Sci., August 1, 2003; 44(8): 3294 - 3300. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. E. Quinn, E. L. Francis, K. S. Nipper, D. I. Flitcroft, G.-s. Ying, R. C. Rees, G. F. Schmid, M. G. Maguire, and R. A. Stone Highly Precise Eye Length Measurements in Children Aged 3 Through 12 Years Arch Ophthalmol, July 1, 2003; 121(7): 985 - 990. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Gwiazda, L. Hyman, M. Hussein, D. Everett, T. T. Norton, D. Kurtz, M. C. Leske, R. Manny, W. Marsh-Tootle, M. Scheiman, et al. A Randomized Clinical Trial of Progressive Addition Lenses versus Single Vision Lenses on the Progression of Myopia in Children Invest. Ophthalmol. Vis. Sci., April 1, 2003; 44(4): 1492 - 1500. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S M Saw, G Gazzard, K-G Au Eong, and D T H Tan Myopia: attempts to arrest progression Br. J. Ophthalmol., November 1, 2002; 86(11): 1306 - 1311. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
