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Change in Full-Field ERGs after Macular Translocation Surgery with 360° Retinotomy

From the Department of Ophthalmology, Nagoya University School of Medicine, Nagoya, Japan.

PURPOSE. One of the methods used in macular translocation (MT) surgery for subfoveal neovascularization is to create a temporary total retinal detachment followed by a 360° retinotomy. The whole retina is then shifted from the original surface of the retinal pigment epithelium (RPE), resulting in an unusual retina and RPE complex. The purpose of this study was to assess retinal function after MT surgery.

METHODS. Full-field electroretinograms (ERGs) were recorded before and 4 to 8 months (mean, 5.4 months) after MT surgery with a 360° retinotomy in 15 consecutive patients with age-related macular degeneration (10 eyes), high myopia (4 eyes), and polypoidal choroidal vasculopathy (1 eye). Their ages ranged from 57 to 74 years. The angle of rotation of the retina ranged from 18° to 45° (mean ± SE, 30 ± 2°). In addition to the recording of the standard rod and mixed rod–cone ERGs after 30 minutes of dark adaptation, the cone single flash and 30-Hz flicker ERGs were recorded immediately after a light-adapting background was turned on (LA₀) and also after 10 minutes of light adaptation (LA₁₀).

RESULTS. The mean amplitude of the full-field ERGs was reduced after surgery by 44% for the rod response, by 24% for the mixed rod–cone b-wave, by 12% and 35% for the cone single-flash b-wave at LA₀ and 30-Hz flicker ERGs at LA₀, respectively. The mean implicit times were delayed by 8 msec for the rod response, by 2 msec for the mixed rod–cone oscillatory potential (OP1), by 4 msec for the cone single-flash b-wave at LA₀, and by 6 msec for the 30-Hz flicker at LA₀.

CONCLUSIONS. These results demonstrated a functional alteration in both the rod and cone components of the ERGs for the entire retina after MT surgery.

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				H. Terasaki, K. Ishikawa, Y. Niwa, C.-H. Piao, T. Niwa, M. Kondo, Y. Ito, and Y. Miyake Changes in Focal Macular ERGs after Macular Translocation Surgery with 360{degrees} Retinotomy Invest. Ophthalmol. Vis. Sci., February 1, 2004; 45(2): 567 - 573. [Abstract] [Full Text] [PDF]

				D Wong, P Stanga, M Briggs, P Lenfestey, E Lancaster, K K Li, K S Lim, and C Groenewald Case selection in macular relocation surgery for age related macular degeneration Br. J. Ophthalmol., February 1, 2004; 88(2): 186 - 190. [Abstract] [Full Text] [PDF]