IOVS Journal of General Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

(Investigative Ophthalmology and Visual Science. 1966;5:22-32.)
© 1966 by The Association for Research in Vision and Ophthalmology, Inc.

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by KAYE, G. I.
Right arrow Articles by TICE, L. W.
Right arrow Search for Related Content
PubMed
Right arrow Articles by KAYE, G. I.
Right arrow Articles by TICE, L. W.

Studies on the Cornea. V. Electron Microscopic Localization of Adenosine Triphosphatase Activity in the Rabbit Cornea in Relation to Transport

GORDON I. KAYE 1 and LOIS W. TICE 2

1 F. Higginson Cabot Laboratory of Electron Microscopy, Division of Surgical Pathology of the Departments of Surgery and Pathology; and the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, N.Y.
2 F. Higginson Cabot Laboratory of Electron Microscopy, Division of Surgical Pathology of the Departments of Surgery and Pathology; and the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, N.Y.; Laboratory of Physical Biology, National Institute of Arthritis and Metabolic Diseases, National Institute of Health, Bethesda, Md.

The distribution of ATPase activity in adult and 7-day-old rabbit corneas has been studied by electron microscopic-histochemical techniques. In the corneal endothelium, the lead phosphate end product of the ATPase reaction is localized at the lateral margins of the cells and in the intercellular spaces. This activity is first demonstrable at 7 days. Pinocytotic vesicles, even those clearly containing ThO2 marker, show no nucleotide phosphatase activity. Epithelial ATPase is less fixation resistant than endothelial ATPase, but, after short glutaraldehyde fixation, end product is localized in the intercellular spaces.

Note:

Recipient of a Career Scientist Award of the Health Research Council of the City of New York under Contract I-320.




This article has been cited by other articles:


Home page
 IOVSHome page
A. H. Conrad, Y. Zhang, A. R. Walker, L. A. Olberding, A. Hanzlick, A. J. Zimmer, R. Morffi, and G. W. Conrad
Thyroxine Affects Expression of KSPG-Related Genes, the Carbonic Anhydrase II Gene, and KS Sulfation in the Embryonic Chicken Cornea
Invest. Ophthalmol. Vis. Sci., January 1, 2006; 47(1): 120 - 132.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1966 by the Association for Research in Vision and Ophthalmology