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(Investigative Ophthalmology and Visual Science. 1966;5:75-80.)
© 1966 by The Association for Research in Vision and Ophthalmology, Inc.

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Ocular Hypersensitivity to Epinephrine

SAMUEL B. ARONSON 1 and EMIKO A. YAMAMOTO 1

1 Eye Research Laboratories, Department of Ophthalmology and the Clinical Laboratories, University of California School of Medicine, of San Francisco General Hospital

The clinical course and degree of disease severity in patients experiencing topical epinephrine hypersensitivity have been classified and correlated with circulating antiepinephrine antibody. The incidence of antiepinephrine antibody has also been studied in two control groups: (1) patients with other external ocular disease and (2) patients with no known ocular disease. Cross-reactivity between epinephrine, phenylephrine, and a triphenylmethane dye have been described.






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