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(Investigative Ophthalmology and Visual Science. 1966;5:610-623.)
© 1966 by The Association for Research in Vision and Ophthalmology, Inc.

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Pressure in the canal of Schlemm and its relation to the site of resistance to outflow of aqueous humor in the eyes of Ethiopian green monkeys

M. L. Sears 1

1 Department of Surgery, Yale University School of Medicine New Haven, Conn.

A simultaneous recording of pressures in the anterior chamber and in the canal of Schlemm in living and dead monkey eyes was used to analyze the site of resistance to outflow of aqueous humor. The results were interpreted to indicate that under the experimental conditions the greatest part of resistance to outflow lay distal to the inner wall of the canal of Schlemm. A value for episcleral venous pressure was obtained by direct measurement. It was also determined that a significant back pressure builds up rapidly with increasing intraocular pressure. Possible sources of error were discussed. Species differences as well as the experimental design and technique may account for the contrasting observations made in human eyes







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