IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

(Investigative Ophthalmology and Visual Science. 1969;8:222-231.)
© 1969 by The Association for Research in Vision and Ophthalmology, Inc.

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by YOUNG, R. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by YOUNG, R. W.

A Difference between Rods and Cones in the Renewal of Outer Segment Protein

RICHARD W. YOUNG 1

1 Department of Anatomy and the Jules Stein Eye Institute, University of California Medical School, Los Angeles, Calif.

The renewal of protein has been studied in the retinal rods and cones of the adult frog by electron microscope autoradiography after injection of radioactive amino acids. In both classes of photoreceptor cells, the synthesis of protein is concentrated in the myoid zone of the inner segment. Newly formed (radioactive) protein is then displaced past the mitochondria of the ellipsoid zone and reaches the outer segment by flowing through the connecting structure. In rods, the labeled protein accumulates at the base of the outer segment, apparently as a component of newly assembled membranous discs, which are then gradually displaced sclerally. In cones, however, no such concentration of radioactive protein has been observed. On the contrary, protein delivered to the outer segment becomes diffusely distributed throughout that structure. TJuis, in the frog, there is a distinct difference between rods and cones in the process of protein renewal.

Key Words: retinal photoreceptor cells • protein synthesis • amino acids • ultrastructure • histology




This article has been cited by other articles:


Home page
 IOVSHome page
C. Bobu, C. M. Craft, M. Masson-Pevet, and D. Hicks
Photoreceptor organization and rhythmic phagocytosis in the nile rat arvicanthis ansorgei: a novel diurnal rodent model for the study of cone pathophysiology.
Invest. Ophthalmol. Vis. Sci., July 1, 2006; 47(7): 3109 - 3118.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
D. Anderson and S. Fisher
Disc shedding in rodlike and conelike photoreceptors of tree squirrels
Science, March 14, 1975; 187(4180): 953 - 955.
[Abstract] [PDF]

Home page
 ScienceHome page
A. M. Laties and P. A. Liebman
Cones of Living Amphibian Eye: Selective Staining
Science, June 19, 1970; 168(3938): 1475 - 1477.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1969 by the Association for Research in Vision and Ophthalmology