New Developments:

Sepideh Zareparsi, Alfred Hero, Donald J. Zack, Robert W. Williams, and Anand Swaroop

Seeing the Unseen: Microarray-Based Gene Expression Profiling in Vision
2004 45: 2457-2462. [Full Text] [PDF]  

Anatomy and Pathology:

Helena Liang, Sheila G. Crewther, David P. Crewther, and Barbara M. Junghans

Structural and Elemental Evidence for Edema in the Retina, Retinal Pigment Epithelium, and Choroid during Recovery from Experimentally Induced Myopia
2004 45: 2463-2474. [Abstract] [Full Text] [PDF]  

Anna N. Ripley, Min S. Chang, and David M. Bader

Bves Is Expressed in the Epithelial Components of the Retina, Lens, and Cornea
2004 45: 2475-2483. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Heather Gear, Hawys Williams, Ewan G. Kemp, and Fiona Roberts

BRAF Mutations in Conjunctival Melanoma
2004 45: 2484-2488. [Abstract] [Full Text] [PDF]  

Hu Huang, Feng Li, Richard A. Alvarez, John D. Ash, and Robert E. Anderson

Downregulation of ATP Synthase Subunit-6, Cytochrome c Oxidase-III, and NADH Dehydrogenase-3 by Bright Cyclic Light in the Rat Retina
2004 45: 2489-2496. [Abstract] [Full Text] [PDF]  

Zai-Long Chi, Seiji Hayasaka, Xue-Yun Zhang, Yoriko Hayasaka, and Hu-Shan Cui

Effects of Rolipram, a Selective Inhibitor of Type 4 Phosphodiesterase, on Lipopolysaccharide-Induced Uveitis in Rats
2004 45: 2497-2502. [Abstract] [Full Text] [PDF]  

Ronald H. Farkas, Jiang Qian, Jeffrey L. Goldberg, Harry A. Quigley, and Donald J. Zack

Gene Expression Profiling of Purified Rat Retinal Ganglion Cells
2004 45: 2503-2513. [Abstract] [Full Text] [PDF] Supplemental Table  

May Nour, Xi-Qin Ding, Heidi Stricker, Steven J. Fliesler, and Muna I. Naash

Modulating Expression of Peripherin/rds in Transgenic Mice: Critical Levels and the Effect of Overexpression
2004 45: 2514-2521. [Abstract] [Full Text] [PDF]  

Deborah C. Otteson, Yuhui Liu, Hong Lai, ChenWei Wang, Susan Gray, Mukesh K. Jain, and Donald J. Zack

Krüppel-like Factor 15, a Zinc-Finger Transcriptional Regulator, Represses the Rhodopsin and Interphotoreceptor Retinoid-Binding Protein Promoters
2004 45: 2522-2530. [Abstract] [Full Text] [PDF]  

Tara C. Murphy, Ramsey A. Saleem, Tim Footz, Robert Ritch, Barbara McGillivray, and Michael A. Walter

The Wing 2 Region of the FOXC1 Forkhead Domain Is Necessary for Normal DNA-Binding and Transactivation Functions
2004 45: 2531-2538. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Hugh R. Taylor, Hien T. V. Vu, Catherine A. McCarty, and Jill E. Keeffe

The Need for Routine Eye Examinations
2004 45: 2539-2542. [Abstract] [Full Text] [PDF]  

Cornea:

Esther Eljarrat-Binstock, Frederik Raiskup, David Stepensky, Abraham J. Domb, and Joseph Frucht-Pery

Delivery of Gentamicin to the Rabbit Eye by Drug-Loaded Hydrogel Iontophoresis
2004 45: 2543-2548. [Abstract] [Full Text] [PDF]  

Jason J. Nichols and P. Ewen King-Smith

The Impact of Hydrogel Lens Settling on the Thickness of the Tears and Contact Lens
2004 45: 2549-2554. [Abstract] [Full Text] [PDF]  

Kamran Hosseini, Alexander I. Kholodnykh, Irina Y. Petrova, Rinat O. Esenaliev, Fred Hendrikse, and Massoud Motamedi

Monitoring of Rabbit Cornea Response to Dehydration Stress by Optical Coherence Tomography
2004 45: 2555-2562. [Abstract] [Full Text] [PDF]  

Kunio Maruyama, Norihiko Yokoi, Akira Takamata, and Shigeru Kinoshita

Effect of Environmental Conditions on Tear Dynamics in Soft Contact Lens Wearers
2004 45: 2563-2568. [Abstract] [Full Text] [PDF]  

Jing Zhang, Hui Li, Jinzhao Wang, Zheng Dong, Shahzad Mian, and Fu-Shin X. Yu

Role of EGFR Transactivation in Preventing Apoptosis in Pseudomonas aeruginosa–Infected Human Corneal Epithelial Cells
2004 45: 2569-2576. [Abstract] [Full Text] [PDF]  

Shizuya Saika, Yasuteru Muragaki, Yuka Okada, Takeshi Miyamoto, Yoshitaka Ohnishi, Akira Ooshima, and Winston W.-Y. Kao

Sonic Hedgehog Expression and Role in Healing Corneal Epithelium
2004 45: 2577-2585. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

David Hui-Kang Ma, Jeng-Yuan Yao, Long-Kuen Yeh, Sung-Tzu Liang, Lai-Chu See, Hui-Ting Chen, Kuei-Ying Lin, Ching-Chung Liang, Ken-Kuo Lin, and Jan-Kan Chen

In Vitro Antiangiogenic Activity in Ex Vivo Expanded Human Limbocorneal Epithelial Cells Cultivated on Human Amniotic Membrane
2004 45: 2586-2595. [Abstract] [Full Text] [PDF]  

Glaucoma:

Pamela A. Sample, Kwokleung Chan, Catherine Boden, Te-Won Lee, Eytan Z. Blumenthal, Robert N. Weinreb, Antje Bernd, John Pascual, Jiucang Hao, Terrence Sejnowski, and Michael H. Goldbaum

Using Unsupervised Learning with Variational Bayesian Mixture of Factor Analysis to Identify Patterns of Glaucomatous Visual Field Defects
2004 45: 2596-2605. [Abstract] [Full Text] [PDF]  

Barry Cense, Teresa C. Chen, B. Hyle Park, Mark C. Pierce, and Johannes F. de Boer

Thickness and Birefringence of Healthy Retinal Nerve Fiber Layer Tissue Measured with Polarization-Sensitive Optical Coherence Tomography
2004 45: 2606-2612. [Abstract] [Full Text] [PDF]  

Jost B. Jonas, Peter Martus, Folkert K. Horn, Anselm Jünemann, Mathias Korth, and Wido M. Budde

Predictive Factors of the Optic Nerve Head for Development or Progression of Glaucomatous Visual Field Loss
2004 45: 2613-2618. [Abstract] [Full Text] [PDF]  

Kirsten H. Eibl, Bernhard Banas, Daniel Kook, Anne V. Ohlmann, Siegfried Priglinger, Anselm Kampik, and Ulrich C. Welge-Luessen

Alkylphosphocholines: A New Therapeutic Option in Glaucoma Filtration Surgery
2004 45: 2619-2624. [Abstract] [Full Text] [PDF]  

William A. Hare, Elizabeth WoldeMussie, Ronald K. Lai, Hau Ton, Guadalupe Ruiz, Teresa Chun, and Larry Wheeler

Efficacy and Safety of Memantine Treatment for Reduction of Changes Associated with Experimental Glaucoma in Monkey, I: Functional Measures
2004 45: 2625-2639. [Abstract] [Full Text] [PDF]  

William A. Hare, Elizabeth WoldeMussie, Robert N. Weinreb, Hau Ton, Guadalupe Ruiz, Mercy Wijono, Barbara Feldmann, Linda Zangwill, and Larry Wheeler

Efficacy and Safety of Memantine Treatment for Reduction of Changes Associated with Experimental Glaucoma in Monkey, II: Structural Measures
2004 45: 2640-2651. [Abstract] [Full Text] [PDF]  

Minoru Obazawa, Yukihiko Mashima, Naoko Sanuki, Setsuko Noda, Jun Kudoh, Nobuyoshi Shimizu, Yoshihisa Oguchi, Yasuhiko Tanaka, and Takeshi Iwata

Analysis of Porcine Optineurin and Myocilin Expression in Trabecular Meshwork Cells and Astrocytes from Optic Nerve Head
2004 45: 2652-2659. [Abstract] [Full Text] [PDF]  

Jost B. Jonas, Eduard Berenshtein, and Leonard Holbach

Lamina Cribrosa Thickness and Spatial Relationships between Intraocular Space and Cerebrospinal Fluid Space in Highly Myopic Eyes
2004 45: 2660-2665. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Claus Cursiefen, Jingtai Cao, Lu Chen, Ying Liu, Kazuichi Maruyama, David Jackson, Friedrich E. Kruse, Stanley J. Wiegand, M. Reza Dana, and J. Wayne Streilein

Inhibition of Hemangiogenesis and Lymphangiogenesis after Normal-Risk Corneal Transplantation by Neutralizing VEGF Promotes Graft Survival
2004 45: 2666-2673. [Abstract] [Full Text] [PDF]  

Jerry Y. Niederkorn, Elizabeth Mayhew, Jessamee Mellon, and Sushma Hegde

Role of Tumor Necrosis Factor Receptor Expression in Anterior Chamber-Associated Immune Deviation (ACAID) and Corneal Allograft Survival
2004 45: 2674-2681. [Abstract] [Full Text] [PDF]  

Lens:

Daniele Tognetto, Giorgia Sanguinetti, Paolo Sirotti, Paolo Cecchini, Luana Marcucci, Enzo Ballone, and Giuseppe Ravalico

Analysis of the Optical Quality of Intraocular Lenses
2004 45: 2682-2690. [Abstract] [Full Text] [PDF]  

Ronald A. Schachar

Qualitative Effect of Zonular Tension on Freshly Extracted Intact Human Crystalline Lenses: Implications for the Mechanism of Accommodation
2004 45: 2691-2695. [Abstract] [Full Text] [PDF]  

Jongkyu Choi, Sun Young Park, and Choun-Ki Joo

Hepatocyte Growth Factor Induces Proliferation of Lens Epithelial Cells through Activation of ERK1/2 and JNK/SAPK
2004 45: 2696-2704. [Abstract] [Full Text] [PDF]  

Phillip A. Wilmarth, Jennifer R. Taube, Michael A. Riviere, Melinda K. Duncan, and Larry L. David

Proteomic and Sequence Analysis of Chicken Lens Crystallins Reveals Alternate Splicing and Translational Forms of ßB2 and ßA2 Crystallins
2004 45: 2705-2715. [Abstract] [Full Text] [PDF]  

Nizar Smaoui, Omar Beltaief, Sonia BenHamed, Ridha M’Rad, Faouzi Maazoul, Amel Ouertani, Habiba Chaabouni, and J. Fielding Hejtmancik

A Homozygous Splice Mutation in the HSF4 Gene Is Associated with an Autosomal Recessive Congenital Cataract
2004 45: 2716-2721. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Hyuncheol Kim, Michael R. Robinson, Martin J. Lizak, Ginger Tansey, Robert J. Lutz, Peng Yuan, Nam S. Wang, and Karl G. Csaky

Controlled Drug Release from an Ocular Implant: An Evaluation Using Dynamic Three-Dimensional Magnetic Resonance Imaging
2004 45: 2722-2731. [Abstract] [Full Text] [PDF]  

B’Ann T. Gabelt, Elizabeth A. Hennes, Jennifer L. Seeman, Baohe Tian, and Paul L. Kaufman

H-7 Effect on Outflow Facility after Trabecular Obstruction Following Long-Term Echothiophate Treatment in Monkeys
2004 45: 2732-2736. [Abstract] [Full Text] [PDF]  

Retina:

Félix Vázquez-Chona, Bong K. Song, and Eldon E. Geisert, Jr

Temporal Changes in Gene Expression after Injury in the Rat Retina
2004 45: 2737-2746. [Abstract] [Full Text] [PDF] Supplemental Files  

Hendrik P. N. Scholl, N. H. Victor Chong, Anthony G. Robson, Graham E. Holder, Anthony T. Moore, and Alan C. Bird

Fundus Autofluorescence in Patients with Leber Congenital Amaurosis
2004 45: 2747-2752. [Abstract] [Full Text] [PDF]  

Cheng Zhang, Bo Lei, Tim T. Lam, Fang Yang, Debasish Sinha, and Mark O. M. Tso

Neuroprotection of Photoreceptors by Minocycline in Light-Induced Retinal Degeneration
2004 45: 2753-2759. [Abstract] [Full Text] [PDF]  

Ahmed M. Abu El-Asrar, Lieve Dralands, Luc Missotten, Ibrahim A. Al-Jadaan, and Karel Geboes

Expression of Apoptosis Markers in the Retinas of Human Subjects with Diabetes
2004 45: 2760-2766. [Abstract] [Full Text] [PDF]  

Dennis S. Rice, Wenhu Huang, Holly A. Jones, Gwenn Hansen, Gui-Lan Ye, Nianha Xu, Elizabeth A. Wilson, Kathy Troughton, Kris Vaddi, Robert C. Newton, Brian P. Zambrowicz, and Arthur T. Sands

Severe Retinal Degeneration Associated with Disruption of Semaphorin 4A
2004 45: 2767-2777. [Abstract] [Full Text] [PDF]  

Timothy L. Jackson, Jost Hillenkamp, Bruce C. Knight, Jin-Jun Zhang, Dhanes Thomas, Miles R. Stanford, and John Marshall

Safety Testing of Indocyanine Green and Trypan Blue Using Retinal Pigment Epithelium and Glial Cell Cultures
2004 45: 2778-2785. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Patric Turowski, Peter Adamson, Julie Sathia, Jin Jun Zhang, Stephen E. Moss, G. William Aylward, Matthew J. Hayes, Naheed Kanuga, and John Greenwood

Basement Membrane-Dependent Modification of Phenotype and Gene Expression in Human Retinal Pigment Epithelial ARPE-19 Cells
2004 45: 2786-2794. [Abstract] [Full Text] [PDF]  

Suzanne Hughes and Tailoi Chan-Ling

Characterization of Smooth Muscle Cell and Pericyte Differentiation in the Rat Retina In Vivo
2004 45: 2795-2806. [Abstract] [Full Text] [PDF]  

Keely M. Bumsted O’Brien, Hong Cheng, Yibin Jiang, Dorothea Schulte, Anand Swaroop, and Anita E. Hendrickson

Expression of Photoreceptor-Specific Nuclear Receptor NR2E3 in Rod Photoreceptors of Fetal Human Retina
2004 45: 2807-2812. [Abstract] [Full Text] [PDF]  

Antonio M. M. Moraes, Cristiano N. Pessôa, Rossiane C. Vommaro, Wanderley De Souza, Fernando G. de Mello, and Jan Nora Hokoç

Cultured Embryonic Retina Systems as a Model for the Study of Underlying Mechanisms of Toxoplasma gondii Infection
2004 45: 2813-2821. [Abstract] [Full Text] [PDF]  

Nataliya Gordiyenko, Maria Campos, Jung Wha Lee, Robert N. Fariss, Jorge Sztein, and Ignacio R. Rodriguez

RPE Cells Internalize Low-Density Lipoprotein (LDL) and Oxidized LDL (oxLDL) in Large Quantities In Vitro and In Vivo
2004 45: 2822-2829. [Abstract] [Full Text] [PDF]  

Ignacio R. Rodriguez, Shahabuddin Alam, and Jung Wha Lee

Cytotoxicity of Oxidized Low-Density Lipoprotein in Cultured RPE Cells Is Dependent on the Formation of 7-Ketocholesterol
2004 45: 2830-2837. [Abstract] [Full Text] [PDF]  

Mark G. Slomiany and Steven A. Rosenzweig

IGF-1–Induced VEGF and IGFBP-3 Secretion Correlates with Increased HIF-1 Expression and Activity in Retinal Pigment Epithelial Cell Line D407
2004 45: 2838-2847. [Abstract] [Full Text] [PDF]  

Jeffery L. King and Clyde Guidry

Insulin-Like Growth Factor Binding Proteins Modulate Müller Cell Responses to Insulin-Like Growth Factors
2004 45: 2848-2855. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Ching-Yu Cheng, May-Yung Yen, Hsin-Yi Lin, Wei-Wei Hsia, and Wen-Ming Hsu

Association of Ocular Dominance and Anisometropic Myopia
2004 45: 2856-2860. [Abstract] [Full Text] [PDF]  

Peter Karwatsky, Olga Overbury, and Jocelyn Faubert

Red-Green Chromatic Mechanisms in Normal Aging and Glaucomatous Observers
2004 45: 2861-2866. [Abstract] [Full Text] [PDF]  

Ari Z. Zivotofsky

The Duncker Illusion: Intersubject Variability, Brief Exposure, and the Role of Eye Movements in Its Generation
2004 45: 2867-2872. [Abstract] [Full Text] [PDF]  

Erratum:

Errata
2004 45: 2474. [Full Text] [PDF]  

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