Lectures:

Stuart L. Fine

Introducing Joshua L. Dunaief, the 2006 Recipient of the Cogan Award
2006 47: 4659. [Full Text] [PDF]  

Joshua L. Dunaief

Iron Induced Oxidative Damage As a Potential Factor in Age-Related Macular Degeneration: The Cogan Lecture
2006 47: 4660-4664. [Abstract] [Full Text] [PDF]  

Joan W. Miller

Introducing Evangelos S. Gragoudas, the 2006 Recipient of the Weisenfeld Award
2006 47: 4665. [Full Text] [PDF]  

Evangelos S. Gragoudas

Proton Beam Irradiation of Uveal Melanomas: The First 30 Years The Weisenfeld Lecture
2006 47: 4666-4673. [Full Text] [PDF]  

Anatomy and Pathology:

Neville A. McBrien, Ravikanth Metlapally, Andrew I. Jobling, and Alex Gentle

Expression of Collagen-Binding Integrin Receptors in the Mammalian Sclera and Their Regulation during the Development of Myopia
2006 47: 4674-4682. [Abstract] [Full Text] [PDF]  

Don Julian De Silva, Ken D. Cocker, Gordon Lau, Simon T. Clay, Alistair R. Fielder, and Merrick J. Moseley

Optic Disk Size and Optic Disk-to-Fovea Distance in Preterm and Full-Term Infants
2006 47: 4683-4686. [Abstract] [Full Text] [PDF]  

Thomas T. Norton, John T. Siegwart, Jr, and Angela O. Amedo

Effectiveness of Hyperopic Defocus, Minimal Defocus, or Myopic Defocus in Competition with a Myopiagenic Stimulus in Tree Shrew Eyes
2006 47: 4687-4699. [Abstract] [Full Text] [PDF]  

Thomas T. Norton, Angela O. Amedo, and John T. Siegwart, Jr

Darkness Causes Myopia in Visually Experienced Tree Shrews
2006 47: 4700-4707. [Abstract] [Full Text] [PDF]  

Andres Bernal, Jean-Marie Parel, and Fabrice Manns

Evidence for Posterior Zonular Fiber Attachment on the Anterior Hyaloid Membrane
2006 47: 4708-4713. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Hemanth Tummala, Manir Ali, Paul Getty, Paul M. Hocking, David W. Burt, Chris F. Inglehearn, and Douglas H. Lester

Mutation in the Guanine Nucleotide–Binding Protein ß-3 Causes Retinal Degeneration and Embryonic Mortality in Chickens
2006 47: 4714-4718. [Abstract] [Full Text] [PDF]  

Ghyslaine Humbert, Cécile Delettre, Audrey Sénéchal, Cécile Bazalgette, Abdelhamid Barakat, Christian Bazalgette, Bernard Arnaud, Guy Lenaers, and Christian P. Hamel

Homozygous Deletion Related to Alu Repeats in RLBP1 Causes Retinitis Punctata Albescens
2006 47: 4719-4724. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Ashok Pandian, Padmaja R. Sankaridurg, Thomas Naduvilath, Daniel O'Leary, Deborah F. Sweeney, Kathryn Rose, and Paul Mitchell

Accommodative Facility in Eyes with and without Myopia
2006 47: 4725-4731. [Abstract] [Full Text] [PDF]  

Ecosse L. Lamoureux, Julie F. Pallant, Konrad Pesudovs, Jennifer B. Hassell, and Jill E. Keeffe

The Impact of Vision Impairment Questionnaire: An Evaluation of Its Measurement Properties using Rasch Analysis
2006 47: 4732-4741. [Abstract] [Full Text] [PDF]  

Rishita Nutheti, Bindiganavale R. Shamanna, Praveen K. Nirmalan, Jill E. Keeffe, Sannapaneni Krishnaiah, Gullapalli N. Rao, and Ravi Thomas

Impact of Impaired Vision and Eye Disease on Quality of Life in Andhra Pradesh
2006 47: 4742-4748. [Abstract] [Full Text] [PDF]  

Mohammad Z. Jadoon, Brendan Dineen, Rupert R. A. Bourne, Shaheen P. Shah, Mohammad A. Khan, Gordon J. Johnson, Clare E. Gilbert, Mohammad D. Khan on behalf of the Pakistan National Eye Survey Study Group

Prevalence of Blindness and Visual Impairment in Pakistan: The Pakistan National Blindness and Visual Impairment Survey
2006 47: 4749-4755. [Abstract] [Full Text] [PDF]  

Mohamed Dirani, Matthew Chamberlain, Sri N. Shekar, Amirul F. M. Islam, Pam Garoufalis, Christine Y. Chen, Robyn H. Guymer, and Paul N. Baird

Heritability of Refractive Error and Ocular Biometrics: The Genes in Myopia (GEM) Twin Study
2006 47: 4756-4761. [Abstract] [Full Text] [PDF]  

Ellen E. Freeman, Beatriz Muñoz, Kathleen A. Turano, and Sheila K. West

Dynamic Measures of Visual Function and Their Relationship to Self-Report of Visual Functioning
2006 47: 4762-4766. [Abstract] [Full Text] [PDF]  

Emily West Gower, Anthony W. Solomon, Matthew J. Burton, Aura Aguirre, Beatriz Muñoz, Robin Bailey, Martin Holland, Pateh Makalo, Patrick Massae, Harran Mkocha, David C. Mabey, and Sheila K. West

Chlamydial Positivity of Nasal Discharge at Baseline Is Associated with Ocular Chlamydial Positivity 2 Months following Azithromycin Treatment
2006 47: 4767-4771. [Abstract] [Full Text] [PDF]  

Mingguang He, Paul J. Foster, Jian Ge, Wenyong Huang, Dandan Wang, David S. Friedman, and Peng T. Khaw

Gonioscopy in Adult Chinese: The Liwan Eye Study
2006 47: 4772-4779. [Abstract] [Full Text] [PDF]  

Cornea:

Satoru Yoshida, Shigeto Shimmura, Tetsuya Kawakita, Hideyuki Miyashita, Seika Den, Jun Shimazaki, and Kazuo Tsubota

Cytokeratin 15 Can Be Used to Identify the Limbal Phenotype in Normal and Diseased Ocular Surfaces
2006 47: 4780-4786. [Abstract] [Full Text] [PDF] Supplementary Figure  

Nirbhai Singh, Pooja D. Jani, Tushar Suthar, Shivan Amin, and Balamurali K. Ambati

Flt-1 Intraceptor Induces the Unfolded Protein Response, Apoptotic Factors, and Regression of Murine Injury–Induced Corneal Neovascularization
2006 47: 4787-4793. [Abstract] [Full Text] [PDF]  

Zhijie Li, Rolando E. Rumbaut, Alan R. Burns, and C. Wayne Smith

Platelet Response to Corneal Abrasion Is Necessary for Acute Inflammation and Efficient Re-epithelialization
2006 47: 4794-4802. [Abstract] [Full Text] [PDF]  

Michiharu Kikuchi, Cheng Zhu, Tadashi Senoo, Yoshitaka Obara, and Nancy C. Joyce

p27kip1 siRNA Induces Proliferation in Corneal Endothelial Cells from Young but Not Older Donors
2006 47: 4803-4809. [Abstract] [Full Text] [PDF]  

Jojo W. Du, Fan Zhang, José E. Capó-Aponte, Souvenir D. Tachado, Jing Zhang, Fu-Shin X. Yu, Robert A. Sack, Henry Koziel, and Peter S. Reinach

AsialoGM1-Mediated IL-8 Release by Human Corneal Epithelial Cells Requires Coexpression of TLR5
2006 47: 4810-4818. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Ivo Schoemaker, Pepijn P. W. Hoefnagel, Tom J. Mastenbroek, Cornelis F. Kolff, Sander Schutte, Frans C. T. van der Helm, Stephen J. Picken, Anton F. C. Gerritsen, Piotr A. Wielopolski, Henk Spekreijse, and Huibert J. Simonsz

Elasticity, Viscosity, and Deformation of Orbital Fat
2006 47: 4819-4826. [Abstract] [Full Text] [PDF] Movie  

Helen V. Danesh-Meyer, Stuart C. Carroll, Rod Foroozan, Peter J. Savino, Jennifer Fan, Yannan Jiang, and Stephen Vander Hoorn

Relationship between Retinal Nerve Fiber Layer and Visual Field Sensitivity as Measured by Optical Coherence Tomography in Chiasmal Compression
2006 47: 4827-4835. [Abstract] [Full Text] [PDF]  

Alison R. Davis, John J. Sloper, Magella M. Neveu, Chris R. Hogg, Michael J. Morgan, and Graham E. Holder

Differential Changes of Magnocellular and Parvocellular Visual Function in Early- and Late-Onset Strabismic Amblyopia
2006 47: 4836-4841. [Abstract] [Full Text] [PDF]  

Armin Breyer, Xiaoyi Jiang, Adrian Rütsche, and Daniel S. Mojon

A New 3D Monitor–Based Random-Dot Stereotest for Children
2006 47: 4842-4846. [Abstract] [Full Text] [PDF]  

Glaucoma:

Gay Mary Verdon-Roe, Mark C. Westcott, Ananth C. Viswanathan, Frederick W. Fitzke, and David F. Garway-Heath

Exploration of the Psychophysics of a Motion Displacement Hyperacuity Stimulus
2006 47: 4847-4855. [Abstract] [Full Text] [PDF]  

Consuelo Gutiérrez-Ortiz, Miguel A. Teus, and Gema Bolivar

Short-Term Effects of Latanoprost on Anterior Chamber Depth in Patients with Glaucoma or Ocular Hypertension
2006 47: 4856-4859. [Abstract] [Full Text] [PDF]  

Pauline A. Radenbaugh, Anju Goyal, Ning C. McLaren, David M. Reed, David C. Musch, Julia E. Richards, and Sayoko E. Moroi

Concordance of Aqueous Humor Flow in the Morning and at Night in Normal Humans
2006 47: 4860-4864. [Abstract] [Full Text] [PDF]  

Yuhei Hasegawa, Junji Nishimura, Naohisa Niiro, Katsuya Hirano, Tatsuro Ishibashi, and Hideo Kanaide

Prostaglandin F₂, but Not Latanoprost, Increases the Ca²⁺ Sensitivity of the Pig Iris Sphincter Muscle
2006 47: 4865-4871. [Abstract] [Full Text] [PDF]  

Zheng He, Bang V. Bui, and Algis J. Vingrys

The Rate of Functional Recovery from Acute IOP Elevation
2006 47: 4872-4880. [Abstract] [Full Text] [PDF]  

Michael Bach, Anke S. Unsoeld, Heiko Philippin, Flemming Staubach, Philip Maier, Hans S. Walter, Thomas G. Bomer, and Jens Funk

Pattern ERG as an Early Glaucoma Indicator in Ocular Hypertension: A Long-Term, Prospective Study
2006 47: 4881-4887. [Abstract] [Full Text] [PDF]  

Joon Mo Kim, Ki Ho Park, Yu Jeong Kim, Hyun Jun Park, and Dong Myung Kim

Thermal Injury Induces Heat Shock Protein in the Optic Nerve Head In Vivo
2006 47: 4888-4894. [Abstract] [Full Text] [PDF]  

Tobias Meyer-ter-Vehn, Sonja Sieprath, Barbara Katzenberger, Susanne Gebhardt, Franz Grehn, and Günther Schlunck

Contractility as a Prerequisite for TGF-ß–Induced Myofibroblast Transdifferentiation in Human Tenon Fibroblasts
2006 47: 4895-4904. [Abstract] [Full Text] [PDF]  

Mika Asai-Coakwell, Christopher Backhouse, Ronald J. Casey, Philip J. Gage, and Ordan J. Lehmann

Reduced Human and Murine Corneal Thickness in an Axenfeld-Rieger Syndrome Subtype
2006 47: 4905-4909. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Xi Huang, Wenjin Du, Sharon A. McClellan, Ronald P. Barrett, and Linda D. Hazlett

TLR4 Is Required for Host Resistance in Pseudomonas aeruginosa Keratitis
2006 47: 4910-4916. [Abstract] [Full Text] [PDF]  

Daniel W. Clarke, Hassan Alizadeh, and Jerry Y. Niederkorn

Intracorneal Instillation of Latex Beads Induces Macrophage-Dependent Protection against Acanthamoeba Keratitis
2006 47: 4917-4925. [Abstract] [Full Text] [PDF]  

Emma B. H. Hume, Nerida Cole, Linda L. Garthwaite, Shamila Khan, and Mark D. P. Willcox

A Protective Role for IL-6 in Staphylococcal Microbial Keratitis
2006 47: 4926-4930. [Abstract] [Full Text] [PDF]  

Lens:

Vladimir N. Simirskii, Robert S. Lee, Eric F. Wawrousek, and Melinda K. Duncan

Inbred FVB/N Mice Are Mutant at the cp49/Bfsp2 Locus and Lack Beaded Filament Proteins in the Lens
2006 47: 4931-4934. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Quteba Ebrahem, Atsushi Minamoto, George Hoppe, Bela Anand-Apte, and Jonathan E. Sears

Triamcinolone Acetonide Inhibits IL-6– and VEGF-Induced Angiogenesis Downstream of the IL-6 and VEGF Receptors
2006 47: 4935-4941. [Abstract] [Full Text] [PDF]  

Timothy L. Jackson, Ali Hussain, Andrea Hodgetts, Ana M. S. Morley, Jost Hillenkamp, Paul M. Sullivan, and John Marshall

Human Scleral Hydraulic Conductivity: Age-Related Changes, Topographical Variation, and Potential Scleral Outflow Facility
2006 47: 4942-4946. [Abstract] [Full Text] [PDF]  

Barbara Link, Anselm Jünemann, Rainer Rix, Otto Sembritzki, Alexander Brenning, Matthias Korth, and Folkert K. Horn

Pupillographic Measurements with Pattern Stimulation: The Pupil’s Response in Normal Subjects and First Measurements in Glaucoma Patients
2006 47: 4947-4955. [Abstract] [Full Text] [PDF]  

Kuai Yu, Yuanyuan Cui, and H. Criss Hartzell

The Bestrophin Mutation A243V, Linked to Adult-Onset Vitelliform Macular Dystrophy, Impairs Its Chloride Channel Function
2006 47: 4956-4961. [Abstract] [Full Text] [PDF]  

Retina:

Akbar Shakoor, Norman P. Blair, Marek Mori, and Mahnaz Shahidi

Chorioretinal Vascular Oxygen Tension Changes in Response to Light Flicker
2006 47: 4962-4965. [Abstract] [Full Text] [PDF]  

Florian Gekeler, Andre Messias, Max Ottinger, Karl Ulrich Bartz-Schmidt, and Eberhart Zrenner

Phosphenes Electrically Evoked with DTL Electrodes: A Study in Patients with Retinitis Pigmentosa, Glaucoma, and Homonymous Visual Field Loss and Normal Subjects
2006 47: 4966-4974. [Abstract] [Full Text] [PDF]  

M. Elizabeth Hartnett, David J. Martiniuk, Yuta Saito, Pete Geisen, Lynda J. Peterson, and Janet R. McColm

Triamcinolone Reduces Neovascularization, Capillary Density and IGF-1 Receptor Phosphorylation in a Model of Oxygen-Induced Retinopathy
2006 47: 4975-4982. [Abstract] [Full Text] [PDF]  

Peter Szurman, Sigrid Roters, Salvatore Grisanti, Sabine Aisenbrey, Ulrich Schraermeyer, Matthias Lüke, Karl Ulrich Bartz-Schmidt, and Gabriele Thumann

Ultrastructural Changes after Artificial Retinal Detachment with Modified Retinal Adhesion
2006 47: 4983-4989. [Abstract] [Full Text] [PDF]  

Siegfried G. Priglinger, Claudia S. Alge, Thomas C. Kreutzer, Aljoscha S. Neubauer, Christos Haritoglou, Anselm Kampik, and Ulrich Welge-Luessen

Keratinocyte Transglutaminase in Proliferative Vitreoretinopathy
2006 47: 4990-4997. [Abstract] [Full Text] [PDF]  

Parykshit Saikia, Tim Maisch, Karin Kobuch, Timothy L. Jackson, Wolfgang Bäumler, Rolf-Markus Szeimies, Veit-Peter Gabel, and Jost Hillenkamp

Safety Testing of Indocyanine Green in an Ex Vivo Porcine Retina Model
2006 47: 4998-5003. [Abstract] [Full Text] [PDF]  

Amir A. Azari, Tomas S. Aleman, Artur V. Cideciyan, Sharon B. Schwartz, Elizabeth A. M. Windsor, Alexander Sumaroka, Andy Y. Cheung, Janet D. Steinberg, Alejandro J. Roman, Edwin M. Stone, Val C. Sheffield, and Samuel G. Jacobson

Retinal Disease Expression in Bardet-Biedl Syndrome-1 (BBS1) Is a Spectrum from Maculopathy to Retina-Wide Degeneration
2006 47: 5004-5010. [Abstract] [Full Text] [PDF]  

Sveinn Hakon Hardarson, Alon Harris, Robert Arnar Karlsson, Gisli Hreinn Halldorsson, Larry Kagemann, Ehud Rechtman, Gunnar Már Zoega, Thor Eysteinsson, Jon Atli Benediktsson, Adalbjorn Thorsteinsson, Peter Koch Jensen, James Beach, and Einar Stefánsson

Automatic Retinal Oximetry
2006 47: 5011-5016. [Abstract] [Full Text] [PDF]  

Bo Chang, Mark S. Dacey, Norm L. Hawes, Peter F. Hitchcock, Ann H. Milam, Pelin Atmaca-Sonmez, Steven Nusinowitz, and John R. Heckenlively

Cone Photoreceptor Function Loss-3, a Novel Mouse Model of Achromatopsia Due to a Mutation in Gnat2
2006 47: 5017-5021. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Lynn W. Maines, Kevin J. French, Ellen B. Wolpert, David A. Antonetti, and Charles D. Smith

Pharmacologic Manipulation of Sphingosine Kinase in Retinal Endothelial Cells: Implications for Angiogenic Ocular Diseases
2006 47: 5022-5031. [Abstract] [Full Text] [PDF]  

Sophie D. Liao and Donald G. Puro

NAD⁺-Induced Vasotoxicity in the Pericyte-Containing Microvasculature of the Rat Retina: Effect of Diabetes
2006 47: 5032-5038. [Abstract] [Full Text] [PDF]  

David Jimeno, Leonard Feiner, Concepcion Lillo, Karen Teofilo, Lawrence S. B. Goldstein, Eric A. Pierce, and David S. Williams

Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre-loxP Knockout of Kif3a with RHO-Cre
2006 47: 5039-5046. [Abstract] [Full Text] [PDF]  

Xiang Q. Werdich and John S. Penn

Specific Involvement of Src Family Kinase Activation in the Pathogenesis of Retinal Neovascularization
2006 47: 5047-5056. [Abstract] [Full Text] [PDF]  

Norbert Kociok, Sven Radetzky, Tim U. Krohne, Claudia Gavranic, and Antonia M. Joussen

Pathological but Not Physiological Retinal Neovascularization Is Altered in TNF-Rp55-Receptor–Deficient Mice
2006 47: 5057-5065. [Abstract] [Full Text] [PDF]  

Lina Liang, Run-Tao Yan, Wenxin Ma, Huanmin Zhang, and Shu-Zhen Wang

Exploring RPE as a Source of Photoreceptors: Differentiation and Integration of Transdifferentiating Cells Grafted into Embryonic Chick Eyes
2006 47: 5066-5074. [Abstract] [Full Text] [PDF]  

Tongalp H. Tezel, Lijun Geng, Henry J. Kaplan, and Lucian V. Del Priore

Retinal Pigment Epithelium Rescues Vascular Endothelium from Retinoic Acid-Induced Apoptosis
2006 47: 5075-5087. [Abstract] [Full Text] [PDF]  

Hong Liu, Sherry Thurig, Othman Mohamed, Daniel Dufort, and Valerie A. Wallace

Mapping Canonical Wnt Signaling in the Developing and Adult Retina
2006 47: 5088-5097. [Abstract] [Full Text] [PDF]  

Suofu Qin, Anne P. McLaughlin, and Gerald W. De Vries

Protection of RPE Cells from Oxidative Injury by 15-Deoxy-^12,14-Prostaglandin J₂ by Augmenting GSH and Activating MAPK
2006 47: 5098-5105. [Abstract] [Full Text] [PDF]  

Nicole S. Harhaj, Edward A. Felinski, Ellen B. Wolpert, Jeffrey M. Sundstrom, Thomas W. Gardner, and David A. Antonetti

VEGF Activation of Protein Kinase C Stimulates Occludin Phosphorylation and Contributes to Endothelial Permeability
2006 47: 5106-5115. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

David J. Ramsey, Harris Ripps, and Haohua Qian

An Electrophysiological Study of Retinal Function in the Diabetic Female Rat
2006 47: 5116-5124. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Marc S. Tibber and Alex J. Shepherd

Transient Tritanopia in Migraine: Evidence for a Large-Field Retinal Abnormality in Blue-Yellow Opponent Pathways
2006 47: 5125-5131. [Abstract] [Full Text] [PDF]  

Tong Li and Howard C. Howland

Role of the Pineal Gland in Ocular Development of the Chick in Normal and Constant Light Conditions
2006 47: 5132-5136. [Abstract] [Full Text] [PDF]  

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