Lectures:

Michael S. Gilmore

Introducing Ilene K. Gipson, the 2007 Recipient of the Friedenwald Award
2007 48: 4390. [Full Text] [PDF]  

Ilene K. Gipson

The Ocular Surface: The Challenge to Enable and Protect Vision: The Friedenwald Lecture
2007 48: 4391-4398. [Full Text] [PDF]  

New Developments:

Elizabeth C. Murphy, Frederick L. Ferris, III, and William R. O’Donnell

An Electronic Medical Records System for Clinical Research and the EMR–EDC Interface
2007 48: 4383-4389. [Full Text] [PDF]  

Anatomy and Pathology:

Vivian Barak, Shahar Frenkel, Klara Valyi-Nagy, Lu Leach, Marsha A. Apushkin, Amy Y. Lin, Inna Kalickman, Nikola A. Baumann, Jacob Pe’er, Andrew J. Maniotis, and Robert Folberg

Using the Direct-Injection Model of Early Uveal Melanoma Hepatic Metastasis to Identify TPS as a Potentially Useful Serum Biomarker
2007 48: 4399-4402. [Abstract] [Full Text] [PDF]  

Efrat Merhavi, Yoram Cohen, Bat Chen R. Avraham, Shahar Frenkel, Itay Chowers, Jacob Pe’er, and Nitza Goldenberg-Cohen

Promoter Methylation Status of Multiple Genes in Uveal Melanoma
2007 48: 4403-4406. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Verline Justilien, Ji-Jing Pang, Kutralanathan Renganathan, Xianquan Zhan, John W. Crabb, So Ra Kim, Janet R. Sparrow, William W. Hauswirth, and Alfred S. Lewin

SOD2 Knockdown Mouse Model of Early AMD
2007 48: 4407-4420. [Abstract] [Full Text] [PDF] Supplementary Figures  

Claire L. Simpson, Pirro Hysi, Shomi S. Bhattacharya, Chris J. Hammond, Andrew Webster, Catherine S. Peckham, Pak C. Sham, and Jugnoo S. Rahi

The Roles of PAX6 and SOX2 in Myopia: Lessons from the 1958 British Birth Cohort
2007 48: 4421-4425. [Abstract] [Full Text] [PDF]  

Shuhei Kawahara, Yasuaki Hata, Muneki Miura, Takeshi Kita, Akihito Sengoku, Shintaro Nakao, Yasutaka Mochizuki, Hiroshi Enaida, Akifumi Ueno, Ali Hafezi-Moghadam, and Tatsuro Ishibashi

Intracellular Events in Retinal Glial Cells Exposed to ICG and BBG
2007 48: 4426-4432. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Christine Y. Chen, Jim Stankovich, Katrina J. Scurrah, Pam Garoufalis, Mohamed Dirani, Kelly K. Pertile, Andrea J. Richardson, and Paul N. Baird

Linkage Replication of the MYP12 Locus in Common Myopia
2007 48: 4433-4439. [Abstract] [Full Text] [PDF]  

Matthew J. Burton, Richard A. Adegbola, Fabakary Kinteh, Usman N. Ikumapayi, Allen Foster, David C. W. Mabey, and Robin L. Bailey

Bacterial Infection and Trachoma in The Gambia: A Case–Control Study
2007 48: 4440-4444. [Abstract] [Full Text] [PDF]  

Ellen E. Freeman, Beatriz Muñoz, Gary Rubin, and Sheila K. West

Visual Field Loss Increases the Risk of Falls in Older Adults: The Salisbury Eye Evaluation
2007 48: 4445-4450. [Abstract] [Full Text] [PDF]  

Cornea:

Michael E. Johnson and Paul J. Murphy

Measurement of Ocular Surface Irritation on a Linear Interval Scale with the Ocular Comfort Index
2007 48: 4451-4458. [Abstract] [Full Text] [PDF] Supplementary Material  

Wolfgang J. Mayer, Ulrike M. Irschick, Patrizia Moser, Martin Wurm, Hartwig P. Huemer, Nikolaus Romani, and Eveline U. Irschick

Characterization of Antigen-Presenting Cells in Fresh and Cultured Human Corneas Using Novel Dendritic Cell Markers
2007 48: 4459-4467. [Abstract] [Full Text] [PDF]  

Hiroshi Toshida, Doan H. Nguyen, Roger W. Beuerman, and Akira Murakami

Evaluation of Novel Dry Eye Model: Preganglionic Parasympathetic Denervation in Rabbit
2007 48: 4468-4475. [Abstract] [Full Text] [PDF]  

Satoru Yamagami, Seiichi Yokoo, Shiro Amano, and Nobuyuki Ebihara

Characterization of Bone Marrow–Derived Cells in the Substantia Propria of the Human Conjunctiva
2007 48: 4476-4481. [Abstract] [Full Text] [PDF]  

Jeanie Chui, Nick Di Girolamo, Minas T. Coroneo, and Denis Wakefield

The Role of Substance P in the Pathogenesis of Pterygia
2007 48: 4482-4489. [Abstract] [Full Text] [PDF]  

Afagh Alavi, Elahe Elahi, Mehdi Hosseini Tehrani, Fahimeh Asadi Amoli, Mohammad-Ali Javadi, Nasrin Rafati, Mohsen Chiani, Setareh Sadat Banihosseini, Behnaz Bayat, Reza Kalhor, and Seyed S. H. Amini

Four Mutations (Three Novel, One Founder) in TACSTD2 among Iranian GDLD Patients
2007 48: 4490-4497. [Abstract] [Full Text] [PDF]  

Ling C. Huang, Rose Y. Reins, Richard L. Gallo, and Alison M. McDermott

Cathelicidin-Deficient (Cnlp^–/–) Mice Show Increased Susceptibility to Pseudomonas aeruginosa Keratitis
2007 48: 4498-4508. [Abstract] [Full Text] [PDF]  

Timothy D. Blalock, Sandra J. Spurr-Michaud, Ann S. Tisdale, Susan R. Heimer, Michael S. Gilmore, Vijaya Ramesh, and Ilene K. Gipson

Functions of MUC16 in Corneal Epithelial Cells
2007 48: 4509-4518. [Abstract] [Full Text] [PDF]  

Noriko Koizumi, Yuji Sakamoto, Naoki Okumura, Norio Okahara, Hideaki Tsuchiya, Ryuzo Torii, Leanne J. Cooper, Yuriko Ban, Hidetoshi Tanioka, and Shigeru Kinoshita

Cultivated Corneal Endothelial Cell Sheet Transplantation in a Primate Model
2007 48: 4519-4526. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Kyoung-Min Lee, Annie P. Lai, James Brodale, and Arthur Jampolsky

Sideslip of the Medial Rectus Muscle during Vertical Eye Rotation
2007 48: 4527-4533. [Abstract] [Full Text] [PDF]  

Walter G. Sannita, Simone Carozzo, Mauro Fioretto, Sergio Garbarino, and Cristina Martinoli

Abnormal Waveform of the Human Pattern VEP: Contribution from Gamma Oscillatory Components
2007 48: 4534-4541. [Abstract] [Full Text] [PDF]  

Sara T. Wester, Joseph F. Rizzo, III, M. David Balkwill, and Conrad Wall, III

Optokinetic Nystagmus as a Measure of Visual Function in Severely Visually Impaired Patients
2007 48: 4542-4548. [Abstract] [Full Text] [PDF]  

Alexander Klistorner, Stuart Graham, Clare Fraser, Raymond Garrick, Tan Nguyen, Michael Paine, Justin O’Day, John Grigg, Hemamalini Arvind, and Frank A. Billson

Electrophysiological Evidence for Heterogeneity of Lesions in Optic Neuritis
2007 48: 4549-4556. [Abstract] [Full Text] [PDF]  

Glaucoma:

Paolo Fogagnolo, Andrew McNaught, Marco Centofanti, Luca Rossetti, and Nicola Orzalesi

The Effects of Intraocular Pressure Reduction on Perimetric Variability in Glaucomatous Eyes
2007 48: 4557-4563. [Abstract] [Full Text] [PDF]  

Maher Saleh, Mahesh Nagaraju, and Vittorio Porciatti

Longitudinal Evaluation of Retinal Ganglion Cell Function and IOP in the DBA/2J Mouse Model of Glaucoma
2007 48: 4564-4572. [Abstract] [Full Text] [PDF]  

Mahesh Nagaraju, Maher Saleh, and Vittorio Porciatti

IOP-Dependent Retinal Ganglion Cell Dysfunction in Glaucomatous DBA/2J Mice
2007 48: 4573-4579. [Abstract] [Full Text] [PDF]  

Quan Liu, Won-Kyu Ju, Jonathan G. Crowston, Fang Xie, George Perry, Mark A. Smith, James D. Lindsey, and Robert N. Weinreb

Oxidative Stress Is an Early Event in Hydrostatic Pressure–Induced Retinal Ganglion Cell Damage
2007 48: 4580-4589. [Abstract] [Full Text] [PDF]  

Hemamalini Arvind, Alexander Klistorner, Stuart Graham, John Grigg, Ivan Goldberg, Asya Klistorner, and Frank A. Billson

Dichoptic Stimulation Improves Detection of Glaucoma with Multifocal Visual Evoked Potentials
2007 48: 4590-4596. [Abstract] [Full Text] [PDF]  

Hongli Yang, J. Crawford Downs, Christopher Girkin, Lisandro Sakata, Anthony Bellezza, Hilary Thompson, and Claude F. Burgoyne

3-D Histomorphometry of the Normal and Early Glaucomatous Monkey Optic Nerve Head: Lamina Cribrosa and Peripapillary Scleral Position and Thickness
2007 48: 4597-4607. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Dass S. Vinay, Jung D. Kim, Tatsuhiko Asai, Beom K. Choi, and Byoung S. Kwon

Absence of 4–1BB Gene Function Exacerbates Lacrimal Gland Inflammation in Autoimmune-Prone MRL-Fas^lpr Mice
2007 48: 4608-4615. [Abstract] [Full Text] [PDF]  

Shao Bo Su, Rafael S. Grajewski, Dror Luger, Rajeev K. Agarwal, Phyllis B. Silver, Jun Tang, Jingsheng Tuo, Chi-Chao Chan, and Rachel R. Caspi

Altered Chemokine Profile Associated with Exacerbated Autoimmune Pathology under Conditions of Genetic Interferon- Deficiency
2007 48: 4616-4625. [Abstract] [Full Text] [PDF]  

Xi Huang, Wenjin Du, Ronald P. Barrett, and Linda D. Hazlett

ST2 Is Essential for Th2 Responsiveness and Resistance to Pseudomonas aeruginosa Keratitis
2007 48: 4626-4633. [Abstract] [Full Text] [PDF]  

Umesh C. S. Yadav, Satish K. Srivastava, and Kota V. Ramana

Aldose Reductase Inhibition Prevents Endotoxin-Induced Uveitis in Rats
2007 48: 4634-4642. [Abstract] [Full Text] [PDF]  

Ilham Bettahi, Anthony B. Nesburn, Susan Yoon, Xiuli Zhang, Amir Mohebbi, Valerie Sue, Aaron Vanderberg, Steven L. Wechsler, and Lbachir BenMohamed

Protective Immunity against Ocular Herpes Infection and Disease Induced by Highly Immunogenic Self-Adjuvanting Glycoprotein D Lipopeptide Vaccines
2007 48: 4643-4653. [Abstract] [Full Text] [PDF]  

Dale S. Gregerson, Neal D. Heuss, Kathleen L. Lew, Scott W. McPherson, and Deborah A. Ferrington

Interaction of Retinal Pigmented Epithelial Cells and CD4 T Cells Leads to T-Cell Anergy
2007 48: 4654-4663. [Abstract] [Full Text] [PDF]  

Ashok Kumar, Jia Yin, Jing Zhang, and Fu-Shin X. Yu

Modulation of Corneal Epithelial Innate Immune Response to Pseudomonas Infection by Flagellin Pretreatment
2007 48: 4664-4670. [Abstract] [Full Text] [PDF]  

Lens:

Rupal H. Trivedi and M. Edward Wilson

Biometry Data from Caucasian and African-American Cataractous Pediatric Eyes
2007 48: 4671-4678. [Abstract] [Full Text] [PDF]  

Norihito Gotoh, Nikole R. Perdue, Hiroyuki Matsushima, E. Helene Sage, Qi Yan, and John I. Clark

An In Vitro Model of Posterior Capsular Opacity: SPARC and TGF-ß2 Minimize Epithelial-to-Mesenchymal Transition in Lens Epithelium
2007 48: 4679-4687. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Anne Katrine Kehler, Kim Holmgaard, Anders Hessellund, Christian Aalkjaer, and Toke Bek

Variable Involvement of the Perivascular Retinal Tissue in Carbonic Anhydrase Inhibitor–Induced Relaxation of Porcine Retinal Arterioles In Vitro
2007 48: 4688-4693. [Abstract] [Full Text] [PDF]  

Kuai Yu, Zhiqiang Qu, Yuanyuan Cui, and H. Criss Hartzell

Chloride Channel Activity of Bestrophin Mutants Associated with Mild or Late-Onset Macular Degeneration
2007 48: 4694-4705. [Abstract] [Full Text] [PDF]  

Retina:

Vassiliki Poulaki, Constantine S. Mitsiades, Vassiliki Kotoula, Joseph Negri, Douglas McMillin, Joan W. Miller, and Nicholas Mitsiades

The Proteasome Inhibitor Bortezomib Induces Apoptosis in Human Retinoblastoma Cell Lines In Vitro
2007 48: 4706-4719. [Abstract] [Full Text] [PDF]  

Linda S. Kim, J. Jason McAnany, Kenneth R. Alexander, and Gerald A. Fishman

Intersession Repeatability of Humphrey Perimetry Measurements in Patients with Retinitis Pigmentosa
2007 48: 4720-4724. [Abstract] [Full Text] [PDF]  

Takeshi Morimoto, Takashi Fujikado, Jun-Sub Choi, Hiroyuki Kanda, Tomomitsu Miyoshi, Yutaka Fukuda, and Yasuo Tano

Transcorneal Electrical Stimulation Promotes the Survival of Photoreceptors and Preserves Retinal Function in Royal College of Surgeons Rats
2007 48: 4725-4732. [Abstract] [Full Text] [PDF]  

Bruce A. Berkowitz, Robin Roberts, John S. Penn, and Marius Gradianu

High-Resolution Manganese-Enhanced MRI of Experimental Retinopathy of Prematurity
2007 48: 4733-4740. [Abstract] [Full Text] [PDF]  

Akihisa Matsubara, Toru Nakazawa, Kosuke Noda, Haicheng She, Edward Connolly, Tara A. Young, Yuichiro Ogura, Evangelos S. Gragoudas, and Joan W. Miller

Photodynamic Therapy Induces Caspase-Dependent Apoptosis in Rat CNV Model
2007 48: 4741-4747. [Abstract] [Full Text] [PDF]  

Saloni Walia, Gerald A. Fishman, Deepak P. Edward, and Martin Lindeman

Retinal Nerve Fiber Layer Defects in RP Patients
2007 48: 4748-4752. [Abstract] [Full Text] [PDF]  

Bruce A. Berkowitz, Robin Roberts, Ann Stemmler, Hongmei Luan, and Marius Gradianu

Impaired Apparent Ion Demand in Experimental Diabetic Retinopathy: Correction by Lipoic Acid
2007 48: 4753-4758. [Abstract] [Full Text] [PDF]  

Tomas S. Aleman, Artur V. Cideciyan, Alexander Sumaroka, Sharon B. Schwartz, Alejandro J. Roman, Elizabeth A. M. Windsor, Janet D. Steinberg, Kari Branham, Mohammad Othman, Anand Swaroop, and Samuel G. Jacobson

Inner Retinal Abnormalities in X-linked Retinitis Pigmentosa with RPGR Mutations
2007 48: 4759-4765. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Li-ping Yang, Xiu-an Zhu, and Mark O. M. Tso

Role of NF-B and MAPKs in Light-Induced Photoreceptor Apoptosis
2007 48: 4766-4776. [Abstract] [Full Text] [PDF]  

Yoshitaka Okawa, Takashi Fujikado, Tomomitsu Miyoshi, Hajime Sawai, Shunji Kusaka, Toshifumi Mihashi, Yoko Hirohara, and Yasuo Tano

Optical Imaging to Evaluate Retinal Activation by Electrical Currents Using Suprachoroidal-Transretinal Stimulation
2007 48: 4777-4784. [Abstract] [Full Text] [PDF]  

Ying Dun, Muthusamy Thangaraju, Puttur Prasad, Vadivel Ganapathy, and Sylvia B. Smith

Prevention of Excitotoxicity in Primary Retinal Ganglion Cells by (+)-Pentazocine, a Sigma Receptor-1–Specific Ligand
2007 48: 4785-4794. [Abstract] [Full Text] [PDF]  

Hiroshi Mochimaru, Norihiro Nagai, Go Hasegawa, Chie Kudo-Saito, Tomonori Yaguchi, Yoshihiko Usui, Toshihide Kurihara, Takashi Koto, Shingo Satofuka, Hajime Shinoda, Yoko Ozawa, Kazuo Tsubota, Yutaka Kawakami, and Susumu Ishida

Suppression of Choroidal Neovascularization by Dendritic Cell Vaccination Targeting VEGFR2
2007 48: 4795-4801. [Abstract] [Full Text] [PDF]  

Javier Ruiz-Ederra and A. S. Verkman

Aquaporin-1–Independent Microvessel Proliferation in a Neonatal Mouse Model of Oxygen-Induced Retinopathy
2007 48: 4802-4810. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Benedetto Falsini, Lucia Ziccardi, Giovanna Stifano, Giancarlo Iarossi, Erasmo Merendino, Angelo M. Minnella, Antonello Fadda, and Emilio Balestrazzi

Temporal Response Properties of the Macular Cone System: Effect of Normal Aging and Age-Related Maculopathy
2007 48: 4811-4817. [Abstract] [Full Text] [PDF]  

Nalini V. Rangaswamy, Suguru Shirato, Muneyoshi Kaneko, Beth I. Digby, John G. Robson, and Laura J. Frishman

Effects of Spectral Characteristics of Ganzfeld Stimuli on the Photopic Negative Response (PhNR) of the ERG
2007 48: 4818-4828. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Wei Shen and Jacob G. Sivak

Eyes of a Lower Vertebrate Are Susceptible to the Visual Environment
2007 48: 4829-4837. [Abstract] [Full Text] [PDF]  

Esther G. González, Luminita Tarita-Nistor, Samuel N. Markowitz, and Martin J. Steinbach

Computer-Based Test to Measure Optimal Visual Acuity in Age-Related Macular Degeneration
2007 48: 4838-4845. [Abstract] [Full Text] [PDF]  

Jenny M. Ip, Son C. Huynh, Annette Kifley, Kathryn A. Rose, Ian G. Morgan, Rohit Varma, and Paul Mitchell

Variation of the Contribution from Axial Length and Other Oculometric Parameters to Refraction by Age and Ethnicity
2007 48: 4846-4853. [Abstract] [Full Text] [PDF]  

Amber M. Barnaby, Ronald M. Hansen, Anne Moskowitz, and Anne B. Fulton

Development of Scotopic Visual Thresholds in Retinopathy of Prematurity
2007 48: 4854-4860. [Abstract] [Full Text] [PDF]  

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