Research Opportunities:

Karl G. Csaky, Elaine A. Richman, and Frederick L. Ferris, III

Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium
2008 49: 479-489. [Full Text] [PDF]  

Anatomy and Pathology:

Janet Y. Tsui, Clifton Dalgard, Kurtis R. Van Quill, Linda Lee, Hans E. Grossniklaus, Henry F. Edelhauser, and Joan M. O'Brien

Subconjunctival Topotecan in Fibrin Sealant in the Treatment of Transgenic Murine Retinoblastoma
2008 49: 490-496. [Abstract] [Full Text] [PDF]  

Mao Ye, Danning Hu, Lili Tu, Xiangtian Zhou, Fan Lu, Bin Wen, Wencan Wu, Yi Lin, Zhonglou Zhou, and Jia Qu

Involvement of PI3K/Akt Signaling Pathway in Hepatocyte Growth Factor–Induced Migration of Uveal Melanoma Cells
2008 49: 497-504. [Abstract] [Full Text] [PDF]  

Willem Maat, Long V. Ly, Ekaterina S. Jordanova, Didi de Wolff-Rouendaal, Nicoline E. Schalij-Delfos, and Martine J. Jager

Monosomy of Chromosome 3 and an Inflammatory Phenotype Occur Together in Uveal Melanoma
2008 49: 505-510. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Rafal Farjo, Ward M. Peterson, and Muna I. Naash

Expression Profiling after Retinal Detachment and Reattachment: A Possible Role for Aquaporin-0
2008 49: 511-521. [Abstract] [Full Text] [PDF] Supplementary Material  

Lanlan Yu, Xiumin Wu, Zhiyong Cheng, Chingwei V. Lee, Jennifer LeCouter, Claudio Campa, Germaine Fuh, Henry Lowman, and Napoleone Ferrara

Interaction between Bevacizumab and Murine VEGF-A: A Reassessment
2008 49: 522-527. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Ecosse L. Lamoreux, Elaine Chong, Jie Jin Wang, Seang Mei Saw, Tin Aung, Paul Mitchell, and Tien Yin Wong

Visual Impairment, Causes of Vision Loss, and Falls: The Singapore Malay Eye Study
2008 49: 528-533. [Abstract] [Full Text] [PDF]  

Mohamed Dirani, Sri N. Shekar, and Paul N. Baird

The Role of Educational Attainment in Refraction: The Genes in Myopia (GEM) Twin Study
2008 49: 534-538. [Abstract] [Full Text] [PDF]  

Cornea:

Zhuo Chen, Louis Tong, Zhijie Li, Kyung-Chul Yoon, Hong Qi, William Farley, De-Quan Li, and Stephen C. Pflugfelder

Hyperosmolarity-Induced Cornification of Human Corneal Epithelial Cells Is Regulated by JNK MAPK
2008 49: 539-549. [Abstract] [Full Text] [PDF]  

Min Zhao, Gilles Thuret, Simone Piselli, Aurelien Pipparelli, Sophie Acquart, Michel Peoc’h, Jean-Marc Dumollard, and Philippe Gain

Use of Poloxamers for Deswelling of Organ-Cultured Corneas
2008 49: 550-559. [Abstract] [Full Text] [PDF]  

Edoardo Villani, Daniela Galimberti, Francesco Viola, Chiara Mapelli, Nicoletta Del Papa, and Roberto Ratiglia

Corneal Involvement in Rheumatoid Arthritis: An In Vivo Confocal Study
2008 49: 560-564. [Abstract] [Full Text] [PDF]  

Kazuhiro Kimura, Shinichiro Teranishi, Ken Fukuda, Koji Kawamoto, and Teruo Nishida

Delayed Disruption of Barrier Function in Cultured Human Corneal Epithelial Cells Induced by Tumor Necrosis Factor- in a Manner Dependent on NF-B
2008 49: 565-571. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Fatema Ghasia, Janice Brunstrom, Mae Gordon, and Lawrence Tychsen

Frequency and Severity of Visual Sensory and Motor Deficits in Children with Cerebral Palsy: Gross Motor Function Classification Scale
2008 49: 572-580. [Abstract] [Full Text] [PDF]  

Christopher M. Knapp, Irene Gottlob, Rebecca J. McLean, and Frank A. Proudlock

Horizontal and Vertical Look and Stare Optokinetic Nystagmus Symmetry in Healthy Adult Volunteers
2008 49: 581-588. [Abstract] [Full Text] [PDF]  

Shegufta J. Farooq, Irene Gottlob, Sherwin Benskin, and Frank A. Proudlock

The Effect of Aging on Torsional Optokinetic Nystagmus
2008 49: 589-593. [Abstract] [Full Text] [PDF]  

Ann L. Webber, Joanne M. Wood, Glen A. Gole, and Brian Brown

The Effect of Amblyopia on Fine Motor Skills in Children
2008 49: 594-603. [Abstract] [Full Text] [PDF]  

Thérèse Collins, Arslan Semroud, Eric Orriols, and Karine Doré-Mazars

Saccade Dynamics before, during, and after Saccadic Adaptation in Humans
2008 49: 604-612. [Abstract] [Full Text] [PDF]  

Glaucoma:

Michael Scholz, Thomas Buder, Silke Seeber, Edyta Adamek, Cord-Michael Becker, and Elke Lütjen-Drecoll

Dependency of Intraocular Pressure Elevation and Glaucomatous Changes in DBA/2J and DBA/2J-Rj Mice
2008 49: 613-621. [Abstract] [Full Text] [PDF]  

Tara Tovar-Vidales, Rouel Roque, Abbot F. Clark, and Robert J. Wordinger

Tissue Transglutaminase Expression and Activity in Normal and Glaucomatous Human Trabecular Meshwork Cells and Tissues
2008 49: 622-628. [Abstract] [Full Text] [PDF]  

Paul Russell, Joshua Z. Gasiorowski, Paul F. Nealy, and Christopher J. Murphy

Response of Human Trabecular Meshwork Cells to Topographic Cues on the Nanoscale Level
2008 49: 629-635. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Haochuan Li, Hassan Alizadeh, and Jerry Y. Niederkorn

Differential Expression of Chemokine Receptors on Uveal Melanoma Cells and Their Metastases
2008 49: 636-643. [Abstract] [Full Text] [PDF]  

Charlette Cain and Thomas E. Phillips

Developmental Changes in Conjunctiva-Associated Lymphoid Tissue of the Rabbit
2008 49: 644-649. [Abstract] [Full Text] [PDF]  

Lens:

Lucy Jean Dawes, Julie Ann Eldred, Ian Kevin Anderson, Matthew Sleeman, John R. Reddan, George Duncan, and Ian Michael Wormstone

TGFβ-Induced Contraction Is Not Promoted by Fibronectin-Fibronectin Receptor Interaction, or SMA Expression
2008 49: 650-661. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Meihua Ju, Carolina Mailhos, John Bradley, Tracy Dowie, Mary Ganley, Gary Cook, Perry Calias, Norbert Lange, Anthony P. Adamis, David T. Shima, and Gregory S. Robinson

Simultaneous but Not Prior Inhibition of VEGF165 Enhances the Efficacy of Photodynamic Therapy in Multiple Models of Ocular Neovascularization
2008 49: 662-670. [Abstract] [Full Text] [PDF] Supplementary Figure  

Anna Ghelli, Anna Maria Porcelli, Claudia Zanna, Andrea Martinuzzi, Valerio Carelli, and Michela Rugolo

Protection against Oxidant-Induced Apoptosis by Exogenous Glutathione in Leber Hereditary Optic Neuropathy Cybrids
2008 49: 671-676. [Abstract] [Full Text] [PDF]  

Elena Abad, Gisela Lorente, Núria Gavara, Miguel Morales, Arcadi Gual, and Xavier Gasull

Activation of Store-Operated Ca²⁺ Channels in Trabecular Meshwork Cells
2008 49: 677-686. [Abstract] [Full Text] [PDF]  

Retina:

Hirokazu Takahashi and Etsuo Chihara

Impact of Diabetic Retinopathy on Quantitative Retinal Nerve Fiber Layer Measurement and Glaucoma Screening
2008 49: 687-692. [Abstract] [Full Text] [PDF]  

Yi-Yu Tsai, Jane-Ming Lin, Lei Wan, Hui-Ju Lin, Yushin Tsai, Cheng-Chun Lee, Chang-Hai Tsai, Fuu-Jen Tsai, and Sung-Huei Tseng

Interleukin Gene Polymorphisms in Age-Related Macular Degeneration
2008 49: 693-698. [Abstract] [Full Text] [PDF]  

Edward D. Gilmore, Chris Hudson, Ravi K. Nrusimhadevara, Rowena Ridout, Patricia T. Harvey, Mark Mandelcorn, Wai-Ching Lam, and Robert G. Devenyi

Retinal Arteriolar Hemodynamic Response to a Combined Isocapnic Hyperoxia and Glucose Provocation in Early Sight-Threatening Diabetic Retinopathy
2008 49: 699-705. [Abstract] [Full Text] [PDF]  

Machelle T. Pardue, Amanda E. Faulkner, Alcides Fernandes, Hang Yin, Frank Schaeffel, Robert W. Williams, Nikita Pozdeyev, and P. Michael Iuvone

High Susceptibility to Experimental Myopia in a Mouse Model with a Retinal ON Pathway Defect
2008 49: 706-712. [Abstract] [Full Text] [PDF]  

Kate Grieve and Austin Roorda

Intrinsic Signals from Human Cone Photoreceptors
2008 49: 713-719. [Abstract] [Full Text] [PDF]  

Zhaoxu Yuan, Travis W. Hein, Robert H. Rosa, Jr, and Lih Kuo

Sildenafil (Viagra) Evokes Retinal Arteriolar Dilation: Dual Pathways via NOS Activation and Phosphodiesterase Inhibition
2008 49: 720-725. [Abstract] [Full Text] [PDF]  

Dimitra Skondra, Kousuke Noda, Lama Almulki, Faryan Tayyari, Sonja Frimmel, Toru Nakazawa, Ivana K. Kim, Souska Zandi, Kennard L. Thomas, Joan W. Miller, Evangelos S. Gragoudas, and Ali Hafezi-Moghadam

Characterization of Azurocidin as a Permeability Factor in the Retina: Involvement in VEGF-Induced and Early Diabetic Blood-Retinal Barrier Breakdown
2008 49: 726-731. [Abstract] [Full Text] [PDF]  

Jingfa Zhang, Yalan Wu, Ying Jin, Fei Ji, Stephen H. Sinclair, Yan Luo, Guoxu Xu, Luo Lu, Wei Dai, Myron Yanoff, Weiye Li, and Guo-Tong Xu

Intravitreal Injection of Erythropoietin Protects both Retinal Vascular and Neuronal Cells in Early Diabetes
2008 49: 732-742. [Abstract] [Full Text] [PDF]  

Aditya Seth, Jing Cui, Eleanor To, Melissa Kwee, and Joanne Matsubara

Complement-Associated Deposits in the Human Retina
2008 49: 743-750. [Abstract] [Full Text] [PDF]  

Bernd Wissinger, Susann Dangel, Herbert Jägle, Lars Hansen, Britta Baumann, Günther Rudolph, Christiane Wolf, Michael Bonin, Katja Koeppen, Thomas Ladewig, Susanne Kohl, Eberhart Zrenner, and Thomas Rosenberg

Cone Dystrophy with Supernormal Rod Response Is Strictly Associated with Mutations in KCNV2
2008 49: 751-757. [Abstract] [Full Text] [PDF]  

Kristel Maaijwee, Tom Missotten, Paul Mulder, and Jan C. van Meurs

Influence of Intraoperative Course on Visual Outcome after an RPE–Choroid Translocation
2008 49: 758-761. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Glyn Chidlow, John P. M. Wood, Jim Manavis, Neville N. Osborne, and Robert J. Casson

Expression of Osteopontin in the Rat Retina: Effects of Excitotoxic and Ischemic Injuries
2008 49: 762-771. [Abstract] [Full Text] [PDF]  

Ji Liu, Wennan Lu, David Reigada, Jonathan Nguyen, Alan M. Laties, and Claire H. Mitchell

Restoration of Lysosomal pH in RPE Cells from Cultured Human and ABCA4^–/– Mice: Pharmacologic Approaches and Functional Recovery
2008 49: 772-780. [Abstract] [Full Text] [PDF]  

Hiroki Kaneko, Koji M. Nishiguchi, Makoto Nakamura, Shu Kachi, and Hiroko Terasaki

Retardation of Photoreceptor Degeneration in the Detached Retina of rd1 Mouse
2008 49: 781-787. [Abstract] [Full Text] [PDF] Supplementary Figure  

David M. Gamm, J. Nicholas Melvan, Rebecca L. Shearer, Isabel Pinilla, Grzegorz Sabat, Clive N. Svendsen, and Lynda S. Wright

A Novel Serum-Free Method for Culturing Human Prenatal Retinal Pigment Epithelial Cells
2008 49: 788-799. [Abstract] [Full Text] [PDF] Supplementary Figures  

Cindy M. L. Hutnik, Cady E. Pocrnich, Hong Liu, Dale W. Laird, and Qing Shao

The Protective Effect of Functional Connexin43 Channels on a Human Epithelial Cell Line Exposed to Oxidative Stress
2008 49: 800-806. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Beatrix Feigl, Ian B. Stewart, Brian Brown, and Andrew J. Zele

Local Neuroretinal Function during Acute Hypoxia in Healthy Older People
2008 49: 807-813. [Abstract] [Full Text] [PDF]  

Anne B. Fulton, Ronald M. Hansen, and Anne Moskowitz

The Cone Electroretinogram in Retinopathy of Prematurity
2008 49: 814-819. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Desmond M. Connolly, John L. Barbur, Sarah L. Hosking, and Ian R. Moorhead

Mild Hypoxia Impairs Chromatic Sensitivity in the Mesopic Range
2008 49: 820-827. [Abstract] [Full Text] [PDF]  

Sing-Hang Cheung, Christopher S. Kallie, Gordon E. Legge, and Allen M. Y. Cheong

Nonlinear Mixed-Effects Modeling of MNREAD Data
2008 49: 828-835. [Abstract] [Full Text] [PDF]  

Balamurali Vasudevan and Kenneth J. Ciuffreda

Additivity of Near Work–Induced Transient Myopia and Its Decay Characteristics in Different Refractive Groups
2008 49: 836-841. [Abstract] [Full Text] [PDF]  

Erratum:

Kyoung-Min Lee, Annie P. Lai, James Brodale, and Arthur Jampolsky

Erratum in: Sideslip of the Medial Rectus Muscle during Vertical Eye Rotation
2008 49: 527. [Full Text] [PDF]  

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