Anatomy and Pathology:

Willem Maat, Sigrid H. W. Beiboer, Martine J. Jager, Gré P. M. Luyten, Nelleke A. Gruis, and Pieter A. van der Velden

Epigenetic Regulation Identifies RASEF as a Tumor-Suppressor Gene in Uveal Melanoma
2008 49: 1291-1298. [Abstract] [Full Text] [PDF]  

Paul R. van Ginkel, Soesiawati R. Darjatmoko, Dhruv Sareen, Lalita Subramanian, Saswati Bhattacharya, Mary J. Lindstrom, Daniel M. Albert, and Arthur S. Polans

Resveratrol Inhibits Uveal Melanoma Tumor Growth via Early Mitochondrial Dysfunction
2008 49: 1299-1306. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Lionel Bretillon, Niyazi Acar, Mathias W. Seeliger, Mylène Santos, Marie Annick Maire, Pierre Juanéda, Lucy Martine, Stéphane Grégoire, Corinne Joffre, Alain M. Bron, and Catherine Creuzot-Garcher

ApoB100,LDLR^–/– Mice Exhibit Reduced Electroretinographic Response and Cholesteryl Esters Deposits in the Retina
2008 49: 1307-1314. [Abstract] [Full Text] [PDF]  

Maria Garcia-Hoyos, Isabel Lorda-Sanchez, Pilar Gómez-Garre, Cristina Villaverde, Diego Cantalapiedra, Ana Bustamante, Dan Diego-Alvarez, Elena Vallespin, Jesus Gallego-Merlo, Maria Jose Trujillo, Carmen Ramos, and Carmen Ayuso

New Type of Mutations in Three Spanish Families with Choroideremia
2008 49: 1315-1321. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Nina Jacobsen, Hanne Jensen, and Ernst Goldschmidt

Does the Level of Physical Activity in University Students Influence Development and Progression of Myopia?—A 2-Year Prospective Cohort Study
2008 49: 1322-1327. [Abstract] [Full Text] [PDF]  

Antonio Pinna, Giuliana Solinas, Carlo Masia, Angelo Zinellu, Ciriaco Carru, and Arturo Carta

Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Nonarteritic Anterior Ischemic Optic Neuropathy in a Sardinian Population, Italy
2008 49: 1328-1332. [Abstract] [Full Text] [PDF]  

Suh-Yuh Wu, Anselm Hennis, Barbara Nemesure, M. Cristina Leske for the Barbados Eye Studies Group

Impact of Glaucoma, Lens Opacities, and Cataract Surgery on Visual Functioning and Related Quality of Life: The Barbados Eye Studies
2008 49: 1333-1338. [Abstract] [Full Text] [PDF]  

Mohamed Dirani, Amirul Islam, Sri N. Shekar, and Paul N. Baird

Dominant Genetic Effects on Corneal Astigmatism: The Genes in Myopia (GEM) Twin Study
2008 49: 1339-1344. [Abstract] [Full Text] [PDF]  

Shunai Jiang, Siobhan E. Moriarty-Craige, Chun Li, Michael J. Lynn, Jiyang Cai, Dean P. Jones, and Paul Sternberg

Associations of Plasma-Soluble Fas Ligand with Aging and Age-Related Macular Degeneration
2008 49: 1345-1349. [Abstract] [Full Text] [PDF]  

Mingguang He, Bin Liu, Wenyong Huang, Jian Zhang, Qiuxia Yin, Yingfeng Zheng, Dandan Wang, and Jian Ge

Heritability of Optic Disc and Cup Measured by the Heidelberg Retinal Tomography in Chinese: The Guangzhou Twin Eye Study
2008 49: 1350-1355. [Abstract] [Full Text] [PDF]  

Mingguang He, Jian Ge, Dandan Wang, Jian Zhang, Alex W. Hewitt, Yoon-Mi Hur, David A. Mackey, and Paul J. Foster

Heritability of the Iridotrabecular Angle Width Measured by Optical Coherence Tomography in Chinese Children: The Guangzhou Twin Eye Study
2008 49: 1356-1361. [Abstract] [Full Text] [PDF]  

Elena Rochtchina, Jie Jin Wang, Bronwen Taylor, Tien Y. Wong, and Paul Mitchell

Ethnic Variability in Retinal Vessel Caliber: A Potential Source of Measurement Error from Ocular Pigmentation?—The Sydney Childhood Eye Study
2008 49: 1362-1366. [Abstract] [Full Text] [PDF]  

Cornea:

Ken-ichi Miyazaki, Yuka Okada, Osamu Yamanaka, Ai Kitano, Kazuo Ikeda, Shigeyuki Kon, Toshimitsu Uede, Susan R. Rittling, David T. Denhardt, Winston Whei-Yang Kao, and Shizuya Saika

Corneal Wound Healing in an Osteopontin-Deficient Mouse
2008 49: 1367-1375. [Abstract] [Full Text] [PDF]  

Patrick Carrier, Alexandre Deschambeault, Mariève Talbot, Claude J. Giasson, François A. Auger, Sylvain L. Guérin, and Lucie Germain

Characterization of Wound Reepithelialization Using a New Human Tissue-Engineered Corneal Wound Healing Model
2008 49: 1376-1385. [Abstract] [Full Text] [PDF]  

Wei Chen, Xiaobo Zhang, Jingna Zhang, Jinpeng Chen, Shiming Wang, Qinmei Wang, and Jia Qu

A Murine Model of Dry Eye Induced by an Intelligently Controlled Environmental System
2008 49: 1386-1391. [Abstract] [Full Text] [PDF]  

Efdal Yoeruek, Martin S. Spitzer, Olcay Tatar, Tilo Biedermann, Salvatore Grisanti, Matthias Lüke, Karl U. Bartz-Schmidt, and Peter Szurman

Toxic Effects of Recombinant Tissue Plasminogen Activator on Cultured Human Corneal Endothelial Cells
2008 49: 1392-1397. [Abstract] [Full Text] [PDF]  

Marc M. Schulze, Natalie Hutchings, and Trefford L. Simpson

The Use of Fractal Analysis and Photometry to Estimate the Accuracy of Bulbar Redness Grading Scales
2008 49: 1398-1406. [Abstract] [Full Text] [PDF]  

Santosh Khanal, Alan Tomlinson, Angus McFadyen, Charles Diaper, and Kannu Ramaesh

Dry Eye Diagnosis
2008 49: 1407-1414. [Abstract] [Full Text] [PDF]  

Nikolaos S. Tsiklis, George D. Kymionis, George A. Kounis, Irini I. Naoumidi, and Ioannis G. Pallikaris

Photorefractive Keratectomy Using Solid State Laser 213 nm and Excimer Laser 193 nm: A Randomized, Contralateral, Comparative, Experimental Study
2008 49: 1415-1420. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Xiaoyan Shan, Jing Tian, Howard S. Ying, Mark F. Walker, David Guyton, Christian Quaia, Lance M. Optican, Rafael J. Tamargo, and David S. Zee

The Effect of Acute Superior Oblique Palsy on Torsional Optokinetic Nystagmus in Monkeys
2008 49: 1421-1428. [Abstract] [Full Text] [PDF]  

Glaucoma:

Yang Liu, Ji-Ae Ko, Ryoji Yanai, Kazuhiro Kimura, Tai-ichiro Chikama, Takeshi Sagara, and Teruo Nishida

Induction by Latanoprost of Collagen Gel Contraction Mediated by Human Tenon Fibroblasts: Role of Intracellular Signaling Molecules
2008 49: 1429-1436. [Abstract] [Full Text] [PDF]  

Alejandra Bosco, Denise M. Inman, Michael R. Steele, Guangming Wu, Ileana Soto, Nicholas Marsh-Armstrong, Walter C. Hubbard, David J. Calkins, Philip J. Horner, and Monica L. Vetter

Reduced Retina Microglial Activation and Improved Optic Nerve Integrity with Minocycline Treatment in the DBA/2J Mouse Model of Glaucoma
2008 49: 1437-1446. [Abstract] [Full Text] [PDF]  

Yuan He, Kar Wah Leung, Yue-Hong Zhang, Shan Duan, Xiu-Feng Zhong, Ru-Zhang Jiang, Zhan Peng, Joyce Tombran-Tink, and Jian Ge

Mitochondrial Complex I Defect Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants
2008 49: 1447-1458. [Abstract] [Full Text] [PDF]  

Francesca Pasutto, Mandy Krumbiegel, Christian Y. Mardin, Daniela Paoli, Robert Lämmer, Bernhard H. F. Weber, Friedrich E. Kruse, Ursula Schlötzer-Schrehardt, and André Reis

Association of LOXL1 Common Sequence Variants in German and Italian Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma
2008 49: 1459-1463. [Abstract] [Full Text] [PDF]  

Carolin Neumann, Alice Yu, Ulrich Welge-Lüssen, Elke Lütjen-Drecoll, and Marco Birke

The Effect of TGF-β2 on Elastin, Type VI Collagen, and Components of the Proteolytic Degradation System in Human Optic Nerve Astrocytes
2008 49: 1464-1472. [Abstract] [Full Text] [PDF]  

Arthur J. Sit, Cherie B. Nau, Jay W. McLaren, Douglas H. Johnson, and David Hodge

Circadian Variation of Aqueous Dynamics in Young Healthy Adults
2008 49: 1473-1479. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Brandt J. Wiskur, Michael L. Robinson, Allison J. Farrand, Billy D. Novosad, and Michelle C. Callegan

Toward Improving Therapeutic Regimens for Bacillus Endophthalmitis
2008 49: 1480-1487. [Abstract] [Full Text] [PDF]  

Sherrie J. Divito and Robert L. Hendricks

Activated Inflammatory Infiltrate in HSV-1-Infected Corneas without Herpes Stromal Keratitis
2008 49: 1488-1495. [Abstract] [Full Text] [PDF]  

Jean Stiles, Lynn Guptill-Yoran, George E. Moore, and Roman M. Pogranichniy

Effects of -Carrageenan on In Vitro Replication of Feline Herpesvirus and on Experimentally Induced Herpetic Conjunctivitis in Cats
2008 49: 1496-1501. [Abstract] [Full Text] [PDF]  

Sharon A. McClellan, Yunfan Zhang, Ronald P. Barrett, and Linda D. Hazlett

Substance P Promotes Susceptibility to Pseudomonas aeruginosa Keratitis in Resistant Mice: Anti-inflammatory Mediators Downregulated
2008 49: 1502-1511. [Abstract] [Full Text] [PDF]  

Philipp Steven, Jan Rupp, Gereon Hüttmann, Norbert Koop, Carmen Lensing, Horst Laqua, and Andreas Gebert

Experimental Induction and Three-Dimensional Two-Photon Imaging of Conjunctiva-Associated Lymphoid Tissue
2008 49: 1512-1517. [Abstract] [Full Text] [PDF]  

Holly L. Rosenzweig, Tammy M. Martin, Monica M. Jann, Stephen R. Planck, Michael P. Davey, Koichi Kobayashi, Richard A. Flavell, and James T. Rosenbaum

NOD2, the Gene Responsible for Familial Granulomatous Uveitis, in a Mouse Model of Uveitis
2008 49: 1518-1524. [Abstract] [Full Text] [PDF] Supplementary Figures  

Lens:

Oliver Puk, Jana Löster, Claudia Dalke, Dian Soewarto, Helmut Fuchs, Birgit Budde, Peter Nürnberg, Eckhard Wolf, Martin Hrabé de Angelis, and Jochen Graw

Mutation in a Novel Connexin-like Gene (Gjf1) in the Mouse Affects Early Lens Development and Causes a Variable Small-Eye Phenotype
2008 49: 1525-1532. [Abstract] [Full Text] [PDF] Supplementary Table  

Koustav Ganguly, Jack Favor, Angelika Neuhäuser-Klaus, Rodica Sandulache, Oliver Puk, Johannes Beckers, Marion Horsch, Sandra Schädler, Daniela Vogt Weisenhorn, Wolfgang Wurst, and Jochen Graw

Novel Allele of Crybb2 in the Mouse and Its Expression in the Brain
2008 49: 1533-1541. [Abstract] [Full Text] [PDF]  

Xiaoren Chen, Jennifer R. Taube, Vladimir I. Simirskii, Tapan P. Patel, and Melinda K. Duncan

Dual Roles for Prox1 in the Regulation of the Chicken βB1-Crystallin Promoter
2008 49: 1542-1552. [Abstract] [Full Text] [PDF]  

David Shearer, Werner Ens, Ken Standing, and Gunnar Valdimarsson

Posttranslational Modifications in Lens Fiber Connexins Identified by Off-Line-HPLC MALDI-Quadrupole Time-of-Flight Mass Spectrometry
2008 49: 1553-1562. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Benjamin Bakall, Precious McLaughlin, J. Brett Stanton, Youwen Zhang, H. Criss Hartzell, Lihua Y. Marmorstein, and Alan D. Marmorstein

Bestrophin-2 Is Involved in the Generation of Intraocular Pressure
2008 49: 1563-1570. [Abstract] [Full Text] [PDF]  

Retina:

Vivek J. Srinivasan, Bryan K. Monson, Maciej Wojtkowski, Richard A. Bilonick, Iwona Gorczynska, Royce Chen, Jay S. Duker, Joel S. Schuman, and James G. Fujimoto

Characterization of Outer Retinal Morphology with High-Speed, Ultrahigh-Resolution Optical Coherence Tomography
2008 49: 1571-1579. [Abstract] [Full Text] [PDF]  

Tomas S. Aleman, Artur V. Cideciyan, Alexander Sumaroka, Elizabeth A. M. Windsor, Waldo Herrera, D. Alan White, Shalesh Kaushal, Anjani Naidu, Alejandro J. Roman, Sharon B. Schwartz, Edwin M. Stone, and Samuel G. Jacobson

Retinal Laminar Architecture in Human Retinitis Pigmentosa Caused by Rhodopsin Gene Mutations
2008 49: 1580-1590. [Abstract] [Full Text] [PDF]  

Yuta Saito, Abhineet Uppal, Grace Byfield, Steven Budd, and M. Elizabeth Hartnett

Activated NAD(P)H Oxidase from Supplemental Oxygen Induces Neovascularization Independent of VEGF in Retinopathy of Prematurity Model
2008 49: 1591-1598. [Abstract] [Full Text] [PDF]  

Jelena Kezic, Heping Xu, Holly R. Chinnery, Connor C. Murphy, and Paul G. McMenamin

Retinal Microglia and Uveal Tract Dendritic Cells and Macrophages Are Not CX3CR1 Dependent in Their Recruitment and Distribution in the Young Mouse Eye
2008 49: 1599-1608. [Abstract] [Full Text] [PDF]  

Christoph Tappeiner, Daniel Barthelmes, Mathias H. Abegg, Sebastian Wolf, and Johannes C. Fleischhauer

Impact of Optic Media Opacities and Image Compression on Quantitative Analysis of Optical Coherence Tomography
2008 49: 1609-1614. [Abstract] [Full Text] [PDF]  

Michael L. Ko, Yilin Liu, Liheng Shi, Dorothy Trump, and Gladys Y.-P. Ko

Circadian Regulation of Retinoschisin in the Chick Retina
2008 49: 1615-1621. [Abstract] [Full Text] [PDF]  

Jason S. Ng, Marcus A. Bearse, Jr, Marilyn E. Schneck, Shirin Barez, and Anthony J. Adams

Local Diabetic Retinopathy Prediction by Multifocal ERG Delays over 3 Years
2008 49: 1622-1628. [Abstract] [Full Text] [PDF]  

Kristel Maaijwee, Twan Koolen, Dagmar Rosenbrand, Elmer Jacobs, Sander Kleinheerenbrink, Arjan Knulst, Joop Bos, Wim P. Holland, Alex Brouwer, Jan C. van Meurs, and Sander Schutte

Threshold Amplitude and Frequency for Ocular Tissue Release from a Vibrating Instrument: An Experimental Study
2008 49: 1629-1632. [Abstract] [Full Text] [PDF]  

Marianne Berdugo, Riad A. Bejjani, Fatemeh Valamanesh, Michele Savoldelli, Jean-Claude Jeanny, Dominique Blanc, Herve Ficheux, Avigdor Scherz, Yoram Salomon, David BenEzra, and Francine Behar-Cohen

Evaluation of the New Photosensitizer Stakel (WST-11) for Photodynamic Choroidal Vessel Occlusion in Rabbit and Rat Eyes
2008 49: 1633-1644. [Abstract] [Full Text] [PDF]  

Renu A. Kowluru, Bindu Menon, and Dennis L. Gierhart

Beneficial Effect of Zeaxanthin on Retinal Metabolic Abnormalities in Diabetic Rats
2008 49: 1645-1651. [Abstract] [Full Text] [PDF]  

Albert O. Edwards, Dequan Chen, Brooke L. Fridley, Katherine M. James, Yanhong Wu, Goncalo Abecasis, Anand Swaroop, Mohammad Othman, Kari Branham, Sudha K. Iyengar, Theru A. Sivakumaran, Ronald Klein, Barbara E. K. Klein, and Nirubol Tosakulwong

Toll-like Receptor Polymorphisms and Age-Related Macular Degeneration
2008 49: 1652-1659. [Abstract] [Full Text] [PDF] Supplementary Tables  

Eva Roomets, Tero Kivelä, and Tiina Tyni

Carnitine Palmitoyltransferase I and Acyl-CoA Dehydrogenase 9 in Retina: Insights of Retinopathy in Mitochondrial Trifunctional Protein Defects
2008 49: 1660-1664. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Kasra A. Rezaei, Yan Chen, Jiyang Cai, and Paul Sternberg

Modulation of Nrf2-Dependent Antioxidant Functions in the RPE by Zip2, a Zinc Transporter Protein
2008 49: 1665-1670. [Abstract] [Full Text] [PDF]  

Ling Wang, Yan Chen, Paul Sternberg, and Jiyang Cai

Essential Roles of the PI3 Kinase/Akt Pathway in Regulating Nrf2-Dependent Antioxidant Functions in the RPE
2008 49: 1671-1678. [Abstract] [Full Text] [PDF]  

Kanako Izumi-Nagai, Norihiro Nagai, Kazuhiro Ohgami, Shingo Satofuka, Yoko Ozawa, Kazuo Tsubota, Shigeaki Ohno, Yuichi Oike, and Susumu Ishida

Inhibition of Choroidal Neovascularization with an Anti-Inflammatory Carotenoid Astaxanthin
2008 49: 1679-1685. [Abstract] [Full Text] [PDF]  

Budd Tucker, Henry Klassen, Liu Yang, Dong Feng Chen, and Michael J. Young

Elevated MMP Expression in the MRL Mouse Retina Creates a Permissive Environment for Retinal Regeneration
2008 49: 1686-1695. [Abstract] [Full Text] [PDF]  

Sandrine Siffroi-Fernandez, Marie-Paule Felder-Schmittbuhl, Hemant Khanna, Anand Swaroop, and David Hicks

FGF19 Exhibits Neuroprotective Effects on Adult Mammalian Photoreceptors In Vitro
2008 49: 1696-1704. [Abstract] [Full Text] [PDF]  

Katsuji Kiuchi, Masato Matsuoka, Jenny C. Wu, Raquel Lima e Silva, Muralitharan Kengatharan, Mary Verghese, Shinji Ueno, Katsutoshi Yokoi, Naw Htee Khu, John P. Cooke, and Peter A. Campochiaro

Mecamylamine Suppresses Basal and Nicotine-Stimulated Choroidal Neovascularization
2008 49: 1705-1711. [Abstract] [Full Text] [PDF]  

Daniel Kook, Armin H. Wolf, Alice L. Yu, Aljoscha S. Neubauer, Siegfried G. Priglinger, Anselm Kampik, and Ulrich C. Welge-Lüssen

The Protective Effect of Quercetin against Oxidative Stress in the Human RPE In Vitro
2008 49: 1712-1720. [Abstract] [Full Text] [PDF]  

Yan Chen, Paul Sternberg, and Jiyang Cai

Characterization of a Bcl-X_L-Interacting Protein FKBP8 and Its Splice Variant in Human RPE Cells
2008 49: 1721-1727. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Deborah M. Little, Keith R. Thulborn, and Janet P. Szlyk

An fMRI Study of Saccadic and Smooth-Pursuit Eye Movement Control in Patients with Age-Related Macular Degeneration
2008 49: 1728-1735. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Norberto López-Gil, Vicente Fernández-Sánchez, Richard Legras, Robert Montés-Micó, Francisco Lara, and Jean Luc Nguyen-Khoa

Accommodation-Related Changes in Monochromatic Aberrations of the Human Eye as a Function of Age
2008 49: 1736-1743. [Abstract] [Full Text] [PDF]  

Erratum:

ERRATUM
2008 49: 1298. [Full Text] [PDF]  

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