Clinical Trials:

Matthew D. Davis, Susan B. Bressler, Lloyd Paul Aiello, Neil M. Bressler, David J. Browning, Christina J. Flaxel, Donald S. Fong, William J. Foster, Adam R. Glassman, Mary Elizabeth R. Hartnett, Craig Kollman, Helen K. Li, Haijing Qin, Ingrid U. Scott, and the Diabetic Retinopathy Clinical Research Network Study Group

Comparison of Time-Domain OCT and Fundus Photographic Assessments of Retinal Thickening in Eyes with Diabetic Macular Edema
2008 49: 1745-1752. First Published on March 3 2008 as doi:10.1167/iovs.07-1257. [Abstract] [Full Text] [PDF] Appendix  

Anatomy and Pathology:

Jin Wook Jeoung, Tae-Woo Kim, Kyung Bok Kang, Jong Joo Lee, Ki Ho Park, and Dong Myung Kim

Overlapping of Retinal Nerve Fibers in the Horizontal Plane
2008 49: 1753-1757. [Abstract] [Full Text] [PDF]  

Noortje I. Regensburg, Pauline H. B. Kok, Frans W. Zonneveld, Lelio Baldeschi, Peerooz Saeed, Wilmar M. Wiersinga, and Maarten P. Mourits

A New and Validated CT-Based Method for the Calculation of Orbital Soft Tissue Volumes
2008 49: 1758-1762. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Rebecca J. Ormsby, Shoba Ranganathan, Joo Chuan Tong, Kim M. Griggs, David P. Dimasi, Alex W. Hewitt, Kathryn P. Burdon, Jamie E. Craig, Josephine Hoh, and David L. Gordon

Functional and Structural Implications of the Complement Factor H Y402H Polymorphism Associated with Age-Related Macular Degeneration
2008 49: 1763-1770. First Published on February 8 2008 as doi:10.1167/iovs.07-1297. [Abstract] [Full Text] [PDF]  

Inderjeet Kaur, Saritha Katta, Avid Hussain, Nazimul Hussain, Annie Mathai, Raja Narayanan, Anjli Hussain, Rajeev K. Reddy, Ajit B. Majji, Taraprasad Das, and Subhabrata Chakrabarti

Variants in the 10q26 Gene Cluster (LOC387715 and HTRA1) Exhibit Enhanced Risk of Age-Related Macular Degeneration along with CFH in Indian Patients
2008 49: 1771-1776. [Abstract] [Full Text] [PDF] Supplementary Material  

Eva Engel, Rüdiger Schraml, Tim Maisch, Karin Kobuch, Burkhard König, Rolf-Markus Szeimies, Jost Hillenkamp, Wolfgang Bäumler, and Rudolf Vasold

Light-Induced Decomposition of Indocyanine Green
2008 49: 1777-1783. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Cong Sun, Gerald Liew, Jie Jin Wang, Paul Mitchell, Seang Mei Saw, Tin Aung, E. Shyong Tai, and Tien Y. Wong

Retinal Vascular Caliber, Blood Pressure, and Cardiovascular Risk Factors in an Asian Population: The Singapore Malay Eye Study
2008 49: 1784-1790. [Abstract] [Full Text] [PDF]  

Birgitte Haargaard, Christian Ritz, Anna Oudin, Jan Wohlfahrt, John Thygesen, Thomas Olsen, and Mads Melbye

Risk of Glaucoma after Pediatric Cataract Surgery
2008 49: 1791-1796. First Published on January 25 2008 as doi:10.1167/iovs.07-1156. [Abstract] [Full Text] [PDF]  

Cornea:

Tomo Suzuki, Frank Schirra, Stephen M. Richards, Roderick V. Jensen, and David A. Sullivan

Estrogen and Progesterone Control of Gene Expression in the Mouse Meibomian Gland
2008 49: 1797-1808. [Abstract] [Full Text] [PDF]  

Mayumi Ueta, Chie Sotozono, Tsutomu Inatomi, Kentaro Kojima, Junji Hamuro, and Shigeru Kinoshita

Association of Combined IL-13/IL-4R Signaling Pathway Gene Polymorphism with Stevens-Johnson Syndrome Accompanied by Ocular Surface Complications
2008 49: 1809-1813. First Published on February 8 2008 as doi:10.1167/iovs.07-1401. [Abstract] [Full Text] [PDF]  

Janine Davis, Dionne Davis, Barbara Norman, and Joram Piatigorsky

Gene Expression of the Mouse Corneal Crystallin Aldh3a1: Activation by Pax6, Oct1, and p300
2008 49: 1814-1826. [Abstract] [Full Text] [PDF] Supplementary Tables  

Joon H. Lee, Min Kim, Young Sun Im, Wungrak Choi, Suk Ho Byeon, and Hyung Keun Lee

NFAT5 Induction and Its Role in Hyperosmolar Stressed Human Limbal Epithelial Cells
2008 49: 1827-1835. [Abstract] [Full Text] [PDF]  

Deniz Hos, Felix Bock, Tina Dietrich, Jasmine Onderka, Friedrich E. Kruse, Karl-Heinz Thierauch, and Claus Cursiefen

Inflammatory Corneal (Lymph)angiogenesis Is Blocked by VEGFR-Tyrosine Kinase Inhibitor ZK 261991, Resulting in Improved Graft Survival after Corneal Transplantation
2008 49: 1836-1842. [Abstract] [Full Text] [PDF]  

Yongqing Liu, Xiaoyan Peng, Jinlian Tan, Douglas S. Darling, Henry J. Kaplan, and Douglas C. Dean

Zeb1 Mutant Mice as a Model of Posterior Corneal Dystrophy
2008 49: 1843-1849. [Abstract] [Full Text] [PDF] Supplementary Table  

Cuiju Xiong, Dong Chen, Jingbo Liu, Bingqian Liu, Naiyang Li, Yang Zhou, Xuanwei Liang, Ping Ma, Chengtian Ye, Jian Ge, and Zhichong Wang

A Rabbit Dry Eye Model Induced by Topical Medication of a Preservative Benzalkonium Chloride
2008 49: 1850-1856. [Abstract] [Full Text] [PDF]  

Shahed Y. Ghoghawala, Mark J. Mannis, Christine E. Pullar, Mark I. Rosenblatt, and R. Rivkah Isseroff

β2-Adrenergic Receptor Signaling Mediates Corneal Epithelial Wound Repair
2008 49: 1857-1863. [Abstract] [Full Text] [PDF]  

Timothy D. Blalock, Sandra J. Spurr-Michaud, Ann S. Tisdale, and Ilene K. Gipson

Release of Membrane-Associated Mucins from Ocular Surface Epithelia
2008 49: 1864-1871. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Michael Richards, Agnes Wong, Paul Foeller, Dolores Bradley, and Lawrence Tychsen

Duration of Binocular Decorrelation Predicts the Severity of Latent (Fusion Maldevelopment) Nystagmus in Strabismic Macaque Monkeys
2008 49: 1872-1878. First Published on January 25 2008 as doi:10.1167/iovs.07-1375. [Abstract] [Full Text] [PDF]  

Helen V. Danesh-Meyer, Taras Papchenko, Peter J. Savino, Andrew Law, James Evans, and Greg D. Gamble

In Vivo Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography Predicts Visual Recovery after Surgery for Parachiasmal Tumors
2008 49: 1879-1885. First Published on February 8 2008 as doi:10.1167/iovs.07-1127. [Abstract] [Full Text] [PDF]  

Glaucoma:

Bao Jian Fan, Dan Yi Wang, Clement Chee Yung Tham, Dennis Shun Chiu Lam, and Chi Pui Pang

Gene Expression Profiles of Human Trabecular Meshwork Cells Induced by Triamcinolone and Dexamethasone
2008 49: 1886-1897. [Abstract] [Full Text] [PDF]  

Luciana M. Alencar, Christopher Bowd, Robert N. Weinreb, Linda M. Zangwill, Pamela A. Sample, and Felipe A. Medeiros

Comparison of HRT-3 Glaucoma Probability Score and Subjective Stereophotograph Assessment for Prediction of Progression in Glaucoma
2008 49: 1898-1906. [Abstract] [Full Text] [PDF]  

Peter A. Aspinall, Zoe K. Johnson, Augusto Azuara-Blanco, Alicia Montarzino, Roger Brice, and Adrian Vickers

Evaluation of Quality of Life and Priorities of Patients with Glaucoma
2008 49: 1907-1915. [Abstract] [Full Text] [PDF]  

Wan-Heng Wang, Loretta G. McNatt, Iok-Hou Pang, Peggy E. Hellberg, John H. Fingert, Mitchell D. McCartney, and Abbot F. Clark

Increased Expression of Serum Amyloid A in Glaucoma and Its Effect on Intraocular Pressure
2008 49: 1916-1923. First Published on January 25 2008 as doi:10.1167/iovs.07-1104. [Abstract] [Full Text] [PDF]  

Jae Hee Kang, Walter C. Willett, Bernard A. Rosner, Susan E. Hankinson, and Louis R. Pasquale

Caffeine Consumption and the Risk of Primary Open-Angle Glaucoma: A Prospective Cohort Study
2008 49: 1924-1931. First Published on February 8 2008 as doi:10.1167/iovs.07-1425. [Abstract] [Full Text] [PDF]  

Yu Zhou, Oleg Grinchuk, and Stanislav I. Tomarev

Transgenic Mice Expressing the Tyr437His Mutant of Human Myocilin Protein Develop Glaucoma
2008 49: 1932-1939. [Abstract] [Full Text] [PDF]  

Yuan Lei, Nigel Garrahan, Boris Hermann, David L. Becker, M. Rosario Hernandez, Michael E. Boulton, and James E. Morgan

Quantification of Retinal Transneuronal Degeneration in Human Glaucoma: A Novel Multiphoton-DAPI Approach
2008 49: 1940-1945. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Lizette M. Cortes, Mary J. Mattapallil, Phyllis B. Silver, Larry A. Donoso, Gregory I. Liou, Wei Zhu, Chi-Chao Chan, and Rachel R. Caspi

Repertoire Analysis and New Pathogenic Epitopes of IRBP in C57BL/6 (H-2^b) and B10.RIII (H-2^r) Mice
2008 49: 1946-1956. [Abstract] [Full Text] [PDF]  

Mary J. Mattapallil, Andrea Augello, Chris Cheadle, Diane Teichberg, Kevin G. Becker, Chi-Chao Chan, Joseph J. Mattapallil, Giuseppina Pennesi, and Rachel R. Caspi

Differentially Expressed Genes in MHC-Compatible Rat Strains That Are Susceptible or Resistant to Experimental Autoimmune Uveitis
2008 49: 1957-1970. First Published on February 15 2008 as doi:10.1167/iovs.07-1295. [Abstract] [Full Text] [PDF]  

Christophe Chiquet, Pierre-Loic Cornut, Yvonne Benito, Gilles Thuret, Max Maurin, Pierre-Olivier Lafontaine, Andre Pechinot, Karine Palombi, Gerard Lina, Alain Bron, Philippe Denis, Anne Carricajo, Catherine Creuzot, Jean-Paul Romanet, Francois Vandenesch for the French Institutional Endophthalmitis Study (FRIENDS) Group

Eubacterial PCR for Bacterial Detection and Identification in 100 Acute Postcataract Surgery Endophthalmitis
2008 49: 1971-1978. [Abstract] [Full Text] [PDF]  

Cynthia A. Cordeiro, Paula R. Moreira, Mariana S. Andrade, Walderez O. Dutra, Wesley R. Campos, Fernando Oréfice, and Antônio L. Teixeira

Interleukin-10 Gene Polymorphism (–1082G/A) is Associated with Toxoplasmic Retinochoroiditis
2008 49: 1979-1982. [Abstract] [Full Text] [PDF]  

Svetlana Hakobyan, Claire L. Harris, Agustín Tortajada, Elena Goicochea de Jorge, Alfredo García-Layana, Patricia Fernández-Robredo, Santiago Rodríguez de Córdoba, and B. Paul Morgan

Measurement of Factor H Variants in Plasma Using Variant-Specific Monoclonal Antibodies: Application to Assessing Risk of Age-Related Macular Degeneration
2008 49: 1983-1990. [Abstract] [Full Text] [PDF]  

Lens:

Karl R. Heys, Michael G. Friedrich, and Roger J. W. Truscott

Free and Bound Water in Normal and Cataractous Human Lenses
2008 49: 1991-1997. [Abstract] [Full Text] [PDF]  

Niranjan Awasthi, Shuh Tuan Wang-Su, and B. J. Wagner

Downregulation of MMP-2 and -9 by Proteasome Inhibition: A Possible Mechanism to Decrease LEC Migration and Prevent Posterior Capsular Opacification
2008 49: 1998-2003. [Abstract] [Full Text] [PDF]  

Dilraj Grewal, Rajeev Jain, Gagandeep Singh Brar, and Satinder Pal Singh Grewal

Pentacam Tomograms: A Novel Method for Quantification of Posterior Capsule Opacification
2008 49: 2004-2008. [Abstract] [Full Text] [PDF]  

Ke Yao, Wei Wu, Yibo Yu, Qunli Zeng, Jiliang He, Deqiang Lu, and Kaijun Wang

Effect of Superposed Electromagnetic Noise on DNA Damage of Lens Epithelial Cells Induced by Microwave Radiation
2008 49: 2009-2015. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Maria de la Fuente, Begoña Seijo, and Maria J. Alonso

Novel Hyaluronic Acid-Chitosan Nanoparticles for Ocular Gene Therapy
2008 49: 2016-2024. [Abstract] [Full Text] [PDF]  

Hyuncheol Kim, Robert N. Fariss, Connie Zhang, Shaun B. Robinson, Michelle Thill, and Karl G. Csaky

Mapping of the Neonatal Fc Receptor in the Rodent Eye
2008 49: 2025-2029. [Abstract] [Full Text] [PDF]  

Alissar Nehmé and Jeffrey Edelman

Dexamethasone Inhibits High Glucose–, TNF-–, and IL-1β–Induced Secretion of Inflammatory and Angiogenic Mediators from Retinal Microvascular Pericytes
2008 49: 2030-2038. [Abstract] [Full Text] [PDF]  

Retina:

Cristiano N. Pessôa, Leticia A. Santiago, Diana A. Santiago, Danielle S. Machado, Fernando A. F. Rocha, Dora F. Ventura, Jan Nora Hokoç, Carmen C. Pazos-Moura, Fredric E. Wondisford, Patricia F. Gardino, and Tania M. Ortiga-Carvalho

Thyroid Hormone Action Is Required for Normal Cone Opsin Expression during Mouse Retinal Development
2008 49: 2039-2045. [Abstract] [Full Text] [PDF]  

Rui Bernardes, Torcato Santos, and José Cunha-Vaz

Increased-Resolution OCT Thickness Mapping of the Human Macula: A Statistically Based Registration
2008 49: 2046-2052. [Abstract] [Full Text] [PDF]  

Taiji Nagaoka, Lih Kuo, Yi Ren, Akitoshi Yoshida, and Travis W. Hein

C-Reactive Protein Inhibits Endothelium-Dependent Nitric Oxide-Mediated Dilation of Retinal Arterioles via Enhanced Superoxide Production
2008 49: 2053-2060. [Abstract] [Full Text] [PDF]  

Daniel X. Hammer, Nicusor V. Iftimia, R. Daniel Ferguson, Chad E. Bigelow, Teoman E. Ustun, Amber M. Barnaby, and Anne B. Fulton

Foveal Fine Structure in Retinopathy of Prematurity: An Adaptive Optics Fourier Domain Optical Coherence Tomography Study
2008 49: 2061-2070. First Published on January 25 2008 as doi:10.1167/iovs.07-1228. [Abstract] [Full Text] [PDF] Movies  

Na Rae Kim, Ju Hee Kang, Oh Woong Kwon, Seok Joon Lee, Jung Hyub Oh, and Hee Seung Chin

Association between Complement Factor H Gene Polymorphisms and Neovascular Age-Related Macular Degeneration in Koreans
2008 49: 2071-2076. First Published on January 25 2008 as doi:10.1167/iovs.07-1195. [Abstract] [Full Text] [PDF]  

Martijn J. Kanis, Robert P. L. Wisse, Tos T. J. M. Berendschot, Jan van de Kraats, and Dirk van Norren

Foveal Cone-Photoreceptor Integrity in Aging Macula Disorder
2008 49: 2077-2081. First Published on January 25 2008 as doi:10.1167/iovs.07-1181. [Abstract] [Full Text] [PDF]  

Isabelle Audo, Michel Michaelides, Anthony G. Robson, Marko Hawlina, Veronika Vaclavik, Jennifer M. Sandbach, Magella M. Neveu, Chris R. Hogg, David M. Hunt, Anthony T. Moore, Alan C. Bird, Andrew R. Webster, and Graham E. Holder

Phenotypic Variation in Enhanced S-cone Syndrome
2008 49: 2082-2093. [Abstract] [Full Text] [PDF]  

Konstantin E. Kotliar, Bruno Mücke, Walthard Vilser, Rudolf Schilling, and Ines M. Lanzl

Effect of Aging on Retinal Artery Blood Column Diameter Measured along the Vessel Axis
2008 49: 2094-2102. [Abstract] [Full Text] [PDF]  

Stacey S. Choi, Robert J. Zawadzki, John L. Keltner, and John S. Werner

Changes in Cellular Structures Revealed by Ultra-high Resolution Retinal Imaging in Optic Neuropathies
2008 49: 2103-2119. [Abstract] [Full Text] [PDF] Supplementary Figures  

Sebastian Thaler, Christos Haritoglou, Tomasz J. Choragiewicz, Andre Messias, Aneta Baryluk, C. Albrecht May, Robert Rejdak, Michal Fiedorowicz, Eberhart Zrenner, and Frank Schuettauf

In Vivo Toxicity Study of Rhodamine 6G in the Rat Retina
2008 49: 2120-2126. [Abstract] [Full Text] [PDF]  

Daisuke Mizuno, Akihisa Matsubara, and Yuichiro Ogura

Effect of Posterior Sub-Tenon Administration of Triamcinolone Acetonide on Leukocyte Dynamics in Rat Retinal Microcirculation after Panretinal Photocoagulation
2008 49: 2127-2133. [Abstract] [Full Text] [PDF]  

John M. Nolan, James M. Stringham, Stephen Beatty, and D. Max Snodderly

Spatial Profile of Macular Pigment and Its Relationship to Foveal Architecture
2008 49: 2134-2142. [Abstract] [Full Text] [PDF]  

Hidenori Takahashi, Hidenobu Ishizaki, Hideaki Tahara, Yasuhiro Tamaki, and Yasuo Yanagi

Suppression of Choroidal Neovascularization by Vaccination with Epitope Peptide Derived from Human VEGF Receptor 2 in an Animal Model
2008 49: 2143-2147. [Abstract] [Full Text] [PDF]  

M. Joe Phillips, Tiffany A. Walker, Hee-Young Choi, Amanda E. Faulkner, Moon K. Kim, Sheree S. Sidney, Amber P. Boyd, John M. Nickerson, Jeffrey H. Boatright, and Machelle T. Pardue

Tauroursodeoxycholic Acid Preservation of Photoreceptor Structure and Function in the rd10 Mouse through Postnatal Day 30
2008 49: 2148-2155. [Abstract] [Full Text] [PDF]  

Daniel Barthelmes, Mark C. Gillies, and Florian K. P. Sutter

Quantitative OCT Analysis of Idiopathic Perifoveal Telangiectasia
2008 49: 2156-2162. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Jun Cai, Oksana Kehoe, Gill M. Smith, Philip Hykin, and Michael E. Boulton

The Angiopoietin/Tie-2 System Regulates Pericyte Survival and Recruitment in Diabetic Retinopathy
2008 49: 2163-2171. [Abstract] [Full Text] [PDF]  

Hiroshi Mochimaru, Tomohiko Usui, Tomonori Yaguchi, Yasuharu Nagahama, Go Hasegawa, Yoshihiko Usui, Shigeto Shimmura, Kazuo Tsubota, Shiro Amano, Yutaka Kawakami, and Susumu Ishida

Suppression of Alkali Burn-Induced Corneal Neovascularization by Dendritic Cell Vaccination Targeting VEGF Receptor 2
2008 49: 2172-2177. First Published on February 8 2008 as doi:10.1167/iovs.07-1396. [Abstract] [Full Text] [PDF]  

Takuya Hasegawa, D. Scott McLeod, Tarl Prow, Carol Merges, Rhonda Grebe, and Gerard A. Lutty

Vascular Precursors in Developing Human Retina
2008 49: 2178-2192. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Koichi Inomata, Kazushige Tsunoda, Gen Hanazono, Yoko Kazato, Kei Shinoda, Mitsuko Yuzawa, Manabu Tanifuji, and Yozo Miyake

Distribution of Retinal Responses Evoked by Transscleral Electrical Stimulation Detected by Intrinsic Signal Imaging in Macaque Monkeys
2008 49: 2193-2200. [Abstract] [Full Text] [PDF]  

Shigeki Machida, Yasutaka Gotoh, Yoshiharu Toba, Aki Ohtaki, Muneyoshi Kaneko, and Daijiro Kurosaka

Correlation between Photopic Negative Response and Retinal Nerve Fiber Layer Thickness and Optic Disc Topography in Glaucomatous Eyes
2008 49: 2201-2207. [Abstract] [Full Text] [PDF]  

Yiu-fai Ng, Henry H. L. Chan, Patrick H. W. Chu, Chi-ho To, Brian C. Gilger, Robert M. Petters, and Fulton Wong

Multifocal Electroretinogram in Rhodopsin P347L Transgenic Pigs
2008 49: 2208-2215. First Published on January 25 2008 as doi:10.1167/iovs.07-1159. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Frank Schaeffel

Binocular Lens Tilt and Decentration Measurements in Healthy Subjects with Phakic Eyes
2008 49: 2216-2222. [Abstract] [Full Text] [PDF]  

2008 E-Abstract First Author Index:

2008 E-ABSTRACT FIRST AUTHOR INDEX
2008 49: 2223-2301. [PDF]  

Erratum:

ERRATUM
2008 49: 1762. [Full Text] [PDF]  

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