Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research June 2023

Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

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Yuanyuan Wang; Mengqi Liu; Zhu Xie; Pengqi Wang; Xiang Li; Xinyuan Yao; Jinmin Tian; Yang Han; Xiangqin Chen; Zhiqiang Xu; Xinjie Mao; Xiangtian Zhou; Jia Qu; Hao Wu
TAGS: chinese (other dialects), chinese people, choroidal circulation, cortical blindness, eye, perfusion, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):7. doi: https://doi.org/10.1167/iovs.64.7.7

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2023

Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

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Arthur G. Fernandes; Palaiologos Alexopoulos; Armando Burgos-Rodriguez; Melween I. Martinez; Mark Ghassibi; Ilya Leskov; Lauren J. N. Brent; Noah Snyder-Mackler; John Danias; Gadi Wollstein; James P. Higham; Amanda D. Melin
TAGS: macaca mulatta, cataract, retinal drusen, eye, body weight
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):3. doi: https://doi.org/10.1167/iovs.64.7.3

Immunology and Microbiology May 2023

Metagenomic Sequencing Analysis Identifies Cross-Cohort Gut Microbial Signatures Associated With Age-Related Macular Degeneration

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Wei Xue; Peiyao Peng; Xiaofeng Wen; Huan Meng; Yali Qin; Tingting Deng; Shixin Guo; Tingting Chen; Xifang Li; Juanran Liang; Feng Zhang; Zhi Xie; Ming Jin; Qiaoxing Liang; Lai Wei
TAGS: age-related macular degeneration, cohort studies, datasets, dysbiosis, microbiome, chinese (other dialects), bacteriophages, chinese people
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):11. doi: https://doi.org/10.1167/iovs.64.5.11

Includes: Supplemental Content

Neuro-ophthalmology May 2023

Visual Field Pointwise Analysis of the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT)

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Susan P. Mollan; Samuel Bodoza; Áine Ní Mhéalóid; James L. Mitchell; Neil R. Miller; Giovanni Montesano; David P. Crabb; Michael Wall; Kristian Brock; Alexandra J. Sinclair
TAGS: body weight, cohort studies, pseudotumor cerebri, visual fields, weight (force)
Trans. Vis. Sci. Tech.. 2023; 12(5):1. doi: https://doi.org/10.1167/tvst.12.5.1

Clinical and Epidemiologic Research April 2023

Contrast Increment and Decrement Processing in Individuals With and Without Diabetes

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Vanessa Thien Sze Tang; Robert Charles Andrew Symons; Spiros Fourlanos; Daryl Guest; Allison Maree McKendrick
TAGS: contrast sensitivity, diabetes mellitus, diabetes mellitus, type 2, reaction time, judgment
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):26. doi: https://doi.org/10.1167/iovs.64.4.26

Clinical and Epidemiologic Research April 2023

The Causal Effect of Education on Myopia: Evidence That More Exposure to Schooling, Rather Than Increased Age, Causes the Onset of Myopia

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Xiaohu Ding; Ian G. Morgan; Yin Hu; Xianghua Tang; Jiayu Zhang; Lan Guo; Yangfeng Guo; Nali Deng; Xueying Du; Yingfeng Zheng; Mingguang He; Ciyong Lu; Xiao Yang; Yizhi Liu
TAGS: educational status, knowledge acquisition, myopia, school (environment)
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):25. doi: https://doi.org/10.1167/iovs.64.4.25

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2023

Potential Choroidal Mechanisms Underlying Atropine's Antimyopic and Rebound Effects: A Mediation Analysis in a Randomized Clinical Trial

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Hannan Xu; Luyao Ye; Yajun Peng; Tao Yu; Shanshan Li; Shijun Weng; Yelin Huang; Yuzhong Chen; Ying Fan; Haidong Zou; Jiangnan He; Jianfeng Zhu; Xun Xu
TAGS: atropine, mediation analysis, myopia, clinical trials, cortical blindness, antidepressive agents, tricyclic, trichloroacetic acid
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):13. doi: https://doi.org/10.1167/iovs.64.4.13

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2023

Prevalence and Characteristics of Peripapillary Gamma Zone in Children With Different Refractive Status: The Hong Kong Children Eye Study

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Xiu Juan Zhang; Duncan Ka Shun Chau; Yu Meng Wang; Cynthia Sze Hang Cheung; Hei-Nga Chan; Jian Shi; Ka Ming Nip; Shumin Tang; Ryan C. F. Chan; Alistair Lau; Sit Hui Kei; Ka Wai Kam; Alvin L. Young; Li Jia Chen; Clement C. Tham; Kyoko Ohno-Matsui; Chi Pui Pang; Jason C. Yam
TAGS: child, eye, hong kong, prevalence
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):4. doi: https://doi.org/10.1167/iovs.64.4.4

Includes: Supplemental Content

Retina March 2023

Racial Disparities in Barriers to Care for Patients With Diabetic Retinopathy in a Nationwide Cohort

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Bonnie B. Huang; Bharanidharan Radha Saseendrakumar; Arash Delavar; Sally L. Baxter
TAGS: cohort studies, diabetic retinopathy, racial disparities, surveys, health services accessibility, social determinants of health, hispanics or latinos, ethnic group
Trans. Vis. Sci. Tech.. 2023; 12(3):14. doi: https://doi.org/10.1167/tvst.12.3.14

Includes: Supplemental Content

Artificial Intelligence March 2023

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

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Vidisha Goyal; A. Thomas Read; Matthew D. Ritch; Bailey G. Hannon; Gabriela Sanchez Rodriguez; Dillon M. Brown; Andrew J. Feola; Adam Hedberg-Buenz; Grant A. Cull; Juan Reynaud; Mona K. Garvin; Michael G. Anderson; Claude F. Burgoyne; C. Ross Ethier
TAGS: axon, datasets, learning
Trans. Vis. Sci. Tech.. 2023; 12(3):9. doi: https://doi.org/10.1167/tvst.12.3.9

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2023

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

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Ella C. Berry; Henry N. Marshall; Sean Mullany; Santiago Diaz Torres; Joshua Schmidt; Daniel Thomson; Lachlan S. W. Knight; Georgina L. Hollitt; Ayub Qassim; Bronwyn Ridge; Angela Schulz; Mark M. Hassall; Thi Thi Nguyen; Stewart Lake; Richard A. Mills; Ashish Agar; Anna Galanopoulos; John Landers; Paul R. Healey; Stuart L. Graham; Alex W. Hewitt; Stuart MacGregor; Robert J. Casson; Owen M. Siggs; Jamie E. Craig
TAGS: cohort studies, physical activity, biobanks
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):11. doi: https://doi.org/10.1167/iovs.64.3.11

Includes: Supplemental Content

Retina February 2023

Associations Between HbA1c Across the Normal Range, Diagnosed, and Undiagnosed Diabetes and Retinal Layer Thickness in UK Biobank Cohort

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Sharon Y.L. Chua; Paul Welsh; Zihan Sun; Konstantinos Balaskas; Alasdair Warwick; David Steel; Sobha Sivaprasad; Roomasa Channa; Tony Ko; Naveed Sattar; Anthony P. Khawaja; Paul J. Foster; Praveen J. Patel; on behalf of The UK Biobank Eye and Vision Consortium
TAGS: biobanks, cohort studies, diabetes mellitus, diabetes mellitus, type 2, hemoglobin a, glycosylated, undiagnosed
Trans. Vis. Sci. Tech.. 2023; 12(2):25. doi: https://doi.org/10.1167/tvst.12.2.25

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2023

Blink Rate Measured In Situ Decreases While Reading From Printed Text or Digital Devices, Regardless of Task Duration, Difficulty, or Viewing Distance

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Ngozi Charity Chidi-Egboka; Isabelle Jalbert; Jiaying Chen; Nancy E. Briggs; Blanka Golebiowski
TAGS: blinking, cell phones, ocular surfaces, reading (activity), signs and symptoms, gait, eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(2):14. doi: https://doi.org/10.1167/iovs.64.2.14

Includes: Supplemental Content

Retina January 2023

Geometric Morphometrics Can Predict Postoperative Visual Acuity Changes in Patients With Epiretinal Membrane: A Retrospective Study

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Sugao Miyagi; Akio Oishi; Eiko Tsuiki; Takashi Kitaoka
TAGS: epiretinal membrane, postoperative care, retrospective studies, shape, visual acuity
Trans. Vis. Sci. Tech.. 2023; 12(1):24. doi: https://doi.org/10.1167/tvst.12.1.24

Clinical and Epidemiologic Research January 2023

Nonpolar Lipids Contribute to Midday Fogging During Scleral Lens Wear

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Maria K. Walker; Laura S. Bailey; Kari B. Basso; Rachel R. Redfern
TAGS: lens (device), lens, crystalline, lipids, sclera
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):7. doi: https://doi.org/10.1167/iovs.64.1.7

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2023

Measuring Retinal Thickness and Visual Acuity in Eyes with Different Types of Astigmatism in a Cohort of Hong Kong Chinese Adults

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Dong Liang; Tsz-Wing Leung; Chea-Su Kee
TAGS: astigmatism, eye, visual acuity, cohort studies, chinese (other dialects), biometry, adult, chinese people, hong kong
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):2. doi: https://doi.org/10.1167/iovs.64.1.2

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2022

Contrast Sensitivity Function: A More Sensitive Index for Assessing Protective Effects of the Cilioretinal Artery on Macular Function in High Myopia

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Ling Wei; Jiaqi Meng; Kaiwen Cheng; Wenwen He; Jiao Qi; Zhong-Lin Lu; Yi Lu; Xiangjia Zhu
TAGS: cilioretinal artery, contrast sensitivity, eye, macular function, myopia, choroid, visual acuity
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):25. doi: https://doi.org/10.1167/iovs.63.13.25

Includes: Supplemental Content

Retina December 2022

Accelerated Peripapillary Retinal Nerve Fiber Layer Degeneration in Patients With Chronic Kidney Disease: A 2-Year Longitudinal Study

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Ling Yeung; I-Wen Wu; Chun-Fu Liu; Yu-Tze Lin; Chin-Chan Lee; Chi-Chin Sun
TAGS: kidney failure, chronic, tissue degeneration, longitudinal studies, retinal nerve fiber layer
Trans. Vis. Sci. Tech.. 2022; 11(12):10. doi: https://doi.org/10.1167/tvst.11.12.10

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2022

Association Between Oral Metformin Use and the Development of Age-Related Macular Degeneration in Diabetic Patients: A Systematic Review and Meta-Analysis

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Kai-Hsiang Liang; Chih-Hao Chen; Hou-Ren Tsai; Chun-Yu Chang; Tai-Li Chen; Wei-Cherng Hsu
TAGS: age-related macular degeneration, diabetes mellitus, meta-analysis, metformin, systematic reviews
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):10. doi: https://doi.org/10.1167/iovs.63.13.10

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2022

Papillary and Peripapillary Hemorrhages in Eyes With Pathologic Myopia

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Jianping Xiong; Ran Du; Shiqi Xie; Hongshuang Lu; Changyu Chen; Tae lgarashi-Yokoi; Kengo Uramoto; Yuka Onishi; Takeshi Yoshida; Koju Kamoi; Kyoko Ohno-Matsui
TAGS: eye, hemorrhage, myopic macular degeneration, glaucoma, recurrence, ophthalmic conus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):28. doi: https://doi.org/10.1167/iovs.63.12.28

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Choroidal Circulation in 8- to 30-Year-Old Chinese, Measured by SS-OCT/OCTA: Relations to Age, Axial Length, and Choroidal Thickness

Age-Related Differences in Ocular Features of a Naturalistic Free-Ranging Population of Rhesus Macaques

Metagenomic Sequencing Analysis Identifies Cross-Cohort Gut Microbial Signatures Associated With Age-Related Macular Degeneration

Visual Field Pointwise Analysis of the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT)

Contrast Increment and Decrement Processing in Individuals With and Without Diabetes

The Causal Effect of Education on Myopia: Evidence That More Exposure to Schooling, Rather Than Increased Age, Causes the Onset of Myopia

Potential Choroidal Mechanisms Underlying Atropine's Antimyopic and Rebound Effects: A Mediation Analysis in a Randomized Clinical Trial

Prevalence and Characteristics of Peripapillary Gamma Zone in Children With Different Refractive Status: The Hong Kong Children Eye Study

Racial Disparities in Barriers to Care for Patients With Diabetic Retinopathy in a Nationwide Cohort

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons

Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study

Associations Between HbA1c Across the Normal Range, Diagnosed, and Undiagnosed Diabetes and Retinal Layer Thickness in UK Biobank Cohort

Blink Rate Measured In Situ Decreases While Reading From Printed Text or Digital Devices, Regardless of Task Duration, Difficulty, or Viewing Distance

Geometric Morphometrics Can Predict Postoperative Visual Acuity Changes in Patients With Epiretinal Membrane: A Retrospective Study

Nonpolar Lipids Contribute to Midday Fogging During Scleral Lens Wear

Measuring Retinal Thickness and Visual Acuity in Eyes with Different Types of Astigmatism in a Cohort of Hong Kong Chinese Adults

Contrast Sensitivity Function: A More Sensitive Index for Assessing Protective Effects of the Cilioretinal Artery on Macular Function in High Myopia

Accelerated Peripapillary Retinal Nerve Fiber Layer Degeneration in Patients With Chronic Kidney Disease: A 2-Year Longitudinal Study

Association Between Oral Metformin Use and the Development of Age-Related Macular Degeneration in Diabetic Patients: A Systematic Review and Meta-Analysis

Papillary and Peripapillary Hemorrhages in Eyes With Pathologic Myopia

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