Cornea

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Anatomy and Pathology/Oncology May 2022

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

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Lei Guo; Rui Hua; Xinxin Zhang; Ting Yu Yan; Yang Tong; Xin Zhao; Shi Chao Chen; Moying Wang; Neil M. Bressler; Jun Kong
TAGS: corneal collagen cross-linking, cross-linking, eye, glaucoma, guinea, sclera, myopia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):24. doi: https://doi.org/10.1167/iovs.63.5.24

Cornea May 2022

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

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Hiroko Nakai; Yoshiki Tsuchiya; Nobuya Koike; Taiki Asano; Morio Ueno; Yasuhiro Umemura; Yuh Sasawaki; Ryutaro Ono; Junji Hamuro; Chie Sotozono; Kazuhiro Yagita
TAGS: circadian clocks, cornea, endothelial cells, gene expression, chronic exertional compartment syndrome, genes, rhythm, bioluminescence
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):16. doi: https://doi.org/10.1167/iovs.63.5.16

Includes: Multimedia, Supplemental Content

Cornea May 2022

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

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Maite López-López; Uxía Regueiro; Susana Belén Bravo; María del Pilar Chantada-Vázquez; Carmen Pena; Elío Díez-Feijoo; Pablo Hervella; Isabel Lema
TAGS: keratoconus, proteins, proteome, proteomics, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):12. doi: https://doi.org/10.1167/iovs.63.5.12

Includes: Supplemental Content

Articles May 2022

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

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Wei Zhang; Alfrun Schönberg; Felix Bock; Claus Cursiefen
TAGS: cd40 ligand, cornea, eye, eyedrops, keratoplasty, rejection (psychology), telomeric repeat amplification protocol, thyroid hormone associated protein complex, allografting, transplantation
Trans. Vis. Sci. Tech.. 2022; 11(5):6. doi: https://doi.org/10.1167/tvst.11.5.6

Includes: Supplemental Content

Cornea May 2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

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Ren Liu; Jing Li; Yue Xu; Ziyan Chen; Huijing Ye; Jinhui Tang; Lai Wei; Lingyi Liang
TAGS: cytokine, epithelial cells, lipogenesis, meibomian gland, melatonin, mitogen-activated protein kinases, proteins, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):6. doi: https://doi.org/10.1167/iovs.63.5.6

Includes: Supplemental Content

Articles May 2022

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

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Keiichi Miyasaka; Masahiko Ayaki; Kazuno Negishi
TAGS: cornea, dry eye syndromes, fluorescein stain method, ocular surfaces, pain, schirmer tear test procedure, signs and symptoms, roc curve, joint meniscus, fluorescein
Trans. Vis. Sci. Tech.. 2022; 11(5):3. doi: https://doi.org/10.1167/tvst.11.5.3

Includes: Supplemental Content

Cornea May 2022

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

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Hui Zhu; Wei Wang; Yongyao Tan; Guanyu Su; Lingjuan Xu; Meng lin Jiang; Shen Li; Yaa-Jyuhn James Meir; Yunming Wang; Guigang Li; Huamin Zhou
TAGS: anaplasia, corneal epithelial cells, epithelial cells, epithelium, cornea, stem cells
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):1. doi: https://doi.org/10.1167/iovs.63.5.1

Includes: Supplemental Content

Cornea April 2022

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

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Junji Hamuro; Kazuko Asada; Morio Ueno; Tomoko Yamashita; Atsushi Mukai; Tomoko Fujita; Eiko Ito; Nao Hiramoto; Munetoyo Toda; Chie Sotozono; Shigeru Kinoshita
TAGS: cd44 antigens, cells, corneal endothelium, gelatinase a, homing-associated cell adhesion molecule, micrornas, mitochondria, patient simulation, prostate health index, protected health information
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):22. doi: https://doi.org/10.1167/iovs.63.4.22

Includes: Supplemental Content

Cornea April 2022

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

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Yu Jeong Kim; Yeji Yeon; Won June Lee; Yong Un Shin; Heeyoon Cho; Han Woong Lim; Min Ho Kang
TAGS: micrornas, epithelial keratitis, simplexvirus, ulcer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):21. doi: https://doi.org/10.1167/iovs.63.4.21

Cornea April 2022

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

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Chunlin Lan; Guo Liu; Longxiang Huang; Xizhen Wang; Junkai Tan; Yun Wang; Ning Fan; Yihua Zhu; Man Yu; Xuyang Liu
TAGS: alkalies, burns, cornea, corneal neovascularization, fibrosis, inflammation, rats
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):14. doi: https://doi.org/10.1167/iovs.63.4.14

Articles April 2022

Prediction of Subjective Refraction From Anterior Corneal Surface, Eye Lengths, and Age Using Machine Learning Algorithms

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Julián Espinosa; Jorge Pérez; Asier Villanueva
TAGS: cornea, eye, machine learning, refraction, spatial vectors, disease vectors
Trans. Vis. Sci. Tech.. 2022; 11(4):8. doi: https://doi.org/10.1167/tvst.11.4.8

Cornea April 2022

Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation

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Kye-Im Jeon; Ankita Kumar; Kaitlin T. Wozniak; Keith Nehrke; Krystel R. Huxlin
TAGS: cornea, fibroblasts, fibrosis, mitochondria, myofibroblasts, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):2. doi: https://doi.org/10.1167/iovs.63.4.2

Includes: Supplemental Content

Articles March 2022

Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea

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Jianfeng Yu; Pengfei Li; Zhuang Li; Yingqi Li; Jiawei Luo; Wenru Su; Dan Liang
TAGS: cornea, macrophages, tofacitinib, allografting, stat1 gene, administration, topical, keratoplasty, rejection (psychology)
Trans. Vis. Sci. Tech.. 2022; 11(3):34. doi: https://doi.org/10.1167/tvst.11.3.34

Cornea March 2022

Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

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Peng Zhang; Lei Tian; Jiayu Bao; Shang Li; Ao Li; Ya Wen; Jingyi Wang; Ying Jie
TAGS: isotretinoin, meibomian gland, meibomian gland dysfunction
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):29. doi: https://doi.org/10.1167/iovs.63.3.29

Articles March 2022

Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus

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Nicolas Alejandre; Pablo Pérez-Merino; Gonzalo Velarde; Ignacio Jiménez-Alfaro; Susana Marcos
TAGS: cornea, eye, ion cyclotron resonance spectrometry, keratoconus, optics, surgical procedures, operative, astigmatism
Trans. Vis. Sci. Tech.. 2022; 11(3):19. doi: https://doi.org/10.1167/tvst.11.3.19

Cornea March 2022

Lacrimal Gland Microenvironment Changes After Obstruction of Lacrimal Gland Ducts

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Xin He; Shaopan Wang; Huimin Sun; Hui He; Yalin Shi; Yiming Wu; Han Wu; Zuguo Liu; Jingyi Zhuang; Wei Li
TAGS: lacrimal duct, lacrimal gland, ligation
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):14. doi: https://doi.org/10.1167/iovs.63.3.14

Includes: Supplemental Content

Articles March 2022

The Impact of Image Quality and Trachomatous Inflammation on Using Photography for Trachoma Prevalence Surveys

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Michelle Odonkor; Fahd Naufal; Harran Mkocha; Nicodemus Funga; Beatriz Muñoz; Sheila K. West
TAGS: image quality, inflammation, photography, surveys, trachoma, mismatch, eye, prevalence
Trans. Vis. Sci. Tech.. 2022; 11(3):11. doi: https://doi.org/10.1167/tvst.11.3.11

Immunology and Microbiology March 2022

The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells

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Andrew R. Griswold; Hsin-Che Huang; Daniel A. Bachovchin
TAGS: cornea, corneal epithelial cells, cytokine, inflammasomes, pyroptosis, value-based purchasing
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):2. doi: https://doi.org/10.1167/iovs.63.3.2

Includes: Supplemental Content

Articles March 2022

Corneal Epithelial Mapping Characteristics in Normal Eyes Using Anterior Segment Spectral Domain Optical Coherence Tomography

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Mohammad Abusamak
TAGS: cornea, epithelium, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2022; 11(3):6. doi: https://doi.org/10.1167/tvst.11.3.6

Includes: Supplemental Content

Cornea March 2022

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

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Chen Chen; Bin Zhang; Junfa Xue; Zongyi Li; Shengqian Dou; Huilin Chen; Qun Wang; Mingli Qu; Huifeng Wang; Yuan Zhang; Luqin Wan; Qingjun Zhou; Lixin Xie
TAGS: cornea, corneal endothelium, diabetes mellitus, endothelial dysfunction, stress, mice, endothelial cells, mitochondria, corneal edema, endoplasmic reticulum
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):4. doi: https://doi.org/10.1167/iovs.63.3.4

Includes: Supplemental Content

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Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

Prediction of Subjective Refraction From Anterior Corneal Surface, Eye Lengths, and Age Using Machine Learning Algorithms

Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation

Topical Administration of 0.3% Tofacitinib Suppresses M1 Macrophage Polarization and Allograft Corneal Rejection by Blocking STAT1 Activation in the Rat Cornea

Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus

Lacrimal Gland Microenvironment Changes After Obstruction of Lacrimal Gland Ducts

The Impact of Image Quality and Trachomatous Inflammation on Using Photography for Trachoma Prevalence Surveys

The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells

Corneal Epithelial Mapping Characteristics in Normal Eyes Using Anterior Segment Spectral Domain Optical Coherence Tomography

Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction

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