Cornea

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Cornea & External Disease December 2023

Fully Automatic, Semiautomatic, and Manual Corneal Nerve Fiber Analysis in Patients With Sarcoidosis

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Lisette R. M. Raasing; Oscar J. M. Vogels; Mirjam Datema; Martijn R. Tannemaat; Marcel Veltkamp; Jan C. Grutters
TAGS: cornea, nerve fibers, neurons, sarcoidosis, fiji
Trans. Vis. Sci. Tech.. 2023; 12(12):3. https://doi.org/10.1167/tvst.12.12.3

Cornea November 2023

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

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Dongyu Li; Xin Jin; Chao Wang; Nan Zhang; Di Jin; Hong Zhang
TAGS: cornea, diabetes mellitus, diabetes mellitus, type 2, microvessels, neurons, perfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):44. https://doi.org/10.1167/iovs.64.14.44

Cornea & External Disease November 2023

Diagnostic Potential of Anterior Segment Optical Coherence Tomography Scans for Pseudomonas Keratitis

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Haidar Khalil; Matthias Bolz; Klemens Waser; Leon Pomberger; Peter Laubichler; Paul Jirak; Nino Hirnschall
TAGS: infiltrates, keratitis, optical coherence tomography, pseudomonas, cornea, body tissue
Trans. Vis. Sci. Tech.. 2023; 12(11):34. https://doi.org/10.1167/tvst.12.11.34

Immunology and Microbiology November 2023

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

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Tejabhiram Yadavalli; Chandrashekhar Patil; Pankaj Sharma; Ipsita Volety; Hemant Borase; Divya Kapoor; Deepak Shukla
TAGS: caviidae, guinea, human herpesvirus 1, infections, recurrence, keratitis, herpetic, cornea, oryctolagus cuniculus, pathology, viruses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):41. https://doi.org/10.1167/iovs.64.14.41

Includes: Supplemental Content

Artificial Intelligence November 2023

AI-Based Decision-Support System for Diagnosing Acanthamoeba Keratitis Using In Vivo Confocal Microscopy Images

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Alisa Lincke; Jenny Roth; António Filipe Macedo; Patrick Bergman; Welf Löwe; Neil S. Lagali
TAGS: acanthamoeba keratitis, cornea, cysts, datasets, microscopy, confocal, training, deep learning, artifacts
Trans. Vis. Sci. Tech.. 2023; 12(11):29. https://doi.org/10.1167/tvst.12.11.29

Cornea November 2023

Endoplasmic Reticulum Stress Disrupts Mitochondrial Bioenergetics, Dynamics and Causes Corneal Endothelial Cell Apoptosis

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Saba Qureshi; Stephanie Lee; William Steidl; Lukas Ritzer; Michael Parise; Ananya Chaubal; Varun Kumar
TAGS: apoptosis, bioenergetics, cornea, endothelial cells, mitochondria, stress, tunicamycin, endoplasmic reticulum, proteins, corneal endothelium
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):18. https://doi.org/10.1167/iovs.64.14.18

Includes: Supplemental Content

Immunology and Microbiology November 2023

NF-κB c-Rel Is a Potential Therapeutic Target for Acute Corneal Transplant Rejection

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Qian Zheng; Ruiling Liu; Bian Jiang; Jijun Sun; Ting Wang; Qingguo Ruan
TAGS: keratoplasty, mice, rejection (psychology), symptom aggravating factors
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):16. https://doi.org/10.1167/iovs.64.14.16

Includes: Supplemental Content

Retina November 2023

Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults

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Shanshan Ge; Yuehua Zhou; Chen Li; Mingxu Zhang
TAGS: adult, chinese (other dialects), chinese people, oxygen saturation measurement, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):13. https://doi.org/10.1167/iovs.64.14.13

Cornea November 2023

Functional Changes of the Ocular Surface Sensory Nerves Due to Contact Lens Use in Young Symptomatic and Asymptomatic Users

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José Ángel Pastor-Zaplana; Juana Gallar; M. Carmen Acosta
TAGS: blinking, cold sensation, common cold, contact lenses, cornea, ocular surfaces, sensory nerves, cold temperature, body temperature, temperature
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):12. https://doi.org/10.1167/iovs.64.14.12

Includes: Supplemental Content

Cornea November 2023

Diabetes-Associated Hyperglycemia Causes Rapid-Onset Ocular Surface Damage

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Judy Weng; Christopher Ross; Jacob Baker; Saleh Alfuraih; Kiumars Shamloo; Ajay Sharma
TAGS: diabetes mellitus, diabetes mellitus, type 2, hyperglycemia, ocular surfaces, mice, cornea, goblet cells, glycocalyx, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):11. https://doi.org/10.1167/iovs.64.14.11

Genetics November 2023

Corneal Vascularization Associated With a Novel PDGFRB Variant

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Titas Gladkauskas; Ove Bruland; Leen Abu Safieh; Deepak P. Edward; Eyvind Rødahl; Cecilie Bredrup
TAGS: corneal neovascularization, genes, ligands, platelet-derived growth factor beta receptor, platelet-derived growth factor, protein-tyrosine kinase inhibitor, glucose
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):9. https://doi.org/10.1167/iovs.64.14.9

Includes: Supplemental Content

Refractive Intervention November 2023

Impact of Single Constant Optimization on the Precision of IOL Power Calculation

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Damien Gatinel; Guillaume Debellemanière; Alain Saad; Avi Wallerstein; Mathieu Gauvin; Radhika Rampat; Jacques Malet
TAGS: precision, cornea, eye, biometry, implants, lens (device)
Trans. Vis. Sci. Tech.. 2023; 12(11):11. https://doi.org/10.1167/tvst.12.11.11

Includes: Supplemental Content

Cornea & External Disease November 2023

A Novel Riboflavin Formulation for Corneal Delivery Without Damaging Epithelial Cells

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Yutaka Yamagata; Takeshi Ide
TAGS: cornea, riboflavin, epithelial cells
Trans. Vis. Sci. Tech.. 2023; 12(11):10. https://doi.org/10.1167/tvst.12.11.10

Artificial Intelligence November 2023

Monitoring the Progression of Clinically Suspected Microbial Keratitis Using Convolutional Neural Networks

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Ming-Tse Kuo; Benny Wei-Yun Hsu; Yi Sheng Lin; Po-Chiung Fang; Hun-Ju Yu; Yu-Ting Hsiao; Vincent S. Tseng
TAGS: keratitis, deep learning, convolutional neural networks, training
Trans. Vis. Sci. Tech.. 2023; 12(11):1. https://doi.org/10.1167/tvst.12.11.1

Cornea November 2023

Interleukin-11 Suppresses Ocular Surface Inflammation and Accelerates Wound Healing

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Aastha Singh; WonKyung J. Cho; Vinay K. Pulimamidi; Sharad K. Mittal; Sunil K. Chauhan
TAGS: inflammation, interleukin-11, cornea, wound healing, wounds and injuries, ocular surfaces
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):1. https://doi.org/10.1167/iovs.64.14.1

Cornea & External Disease October 2023

Establishing a Mouse Model of Chlorpromazine-Induced Corneal Trigeminal Denervation

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Xiongshi Lin; Peipei Xu; Ying Tian; Haiqi Xiao; Xing Dong; Shuangyong Wang
TAGS: chlorpromazine, cornea, denervation, mice
Trans. Vis. Sci. Tech.. 2023; 12(10):21. https://doi.org/10.1167/tvst.12.10.21

Includes: Supplemental Content

Cornea October 2023

Characterization of the Limbal Epithelial Stem Cell Niche

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Isabel Y. Moreno; Arian Parsaie; Tarsis F. Gesteira; Vivien J. Coulson-Thomas
TAGS: cornea, epithelial stem cells, genes, immunohistochemistry, proteins, western blotting
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):48. https://doi.org/10.1167/iovs.64.13.48

Includes: Supplemental Content

Cornea October 2023

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis

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Kye-Im Jeon; Ankita Kumar; Christine L. Callan; Margaret DeMagistris; Scott MacRae; Keith Nehrke; Krystel R. Huxlin
TAGS: cornea, fibrosis, mitochondria, myofibroblasts, phenotype, pyruvates, troglitazone, biological transport, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):36. https://doi.org/10.1167/iovs.64.13.36

Includes: Supplemental Content

Cornea October 2023

Molecular and Phenotypic Characterization of Ocular Methicillin-Resistant Staphylococcus epidermidis Isolates in Taiwan

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Yin-Hsi Chang; Yhu-Chering Huang; Hung-Chi Chen; David H. K. Ma; Lung-Kun Yeh; Kuo-Hsuan Hung; Ching-Hsi Hsiao
TAGS: biofilms, conjunctiva, disease susceptibility, eye infections, methicillin, phenotype, staphylococcus epidermidis, taiwan, virulence, antibiotics
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):33. https://doi.org/10.1167/iovs.64.13.33

Includes: Supplemental Content

Cornea October 2023

Adipose Mesenchymal Stem Cell-Derived Exosomes Promote the Regeneration of Corneal Endothelium Through Ameliorating Senescence

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Yunkyoung Ryu; Jin Sun Hwang; Kyung Bo Noh; Se Hie Park; Je Hyun Seo; Young Joo Shin
TAGS: ambulatory surgery center, exosomes, micrornas, aging, corneal endothelium, hydrogen peroxide
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):29. https://doi.org/10.1167/iovs.64.13.29

Includes: Supplemental Content

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Fully Automatic, Semiautomatic, and Manual Corneal Nerve Fiber Analysis in Patients With Sarcoidosis

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

Diagnostic Potential of Anterior Segment Optical Coherence Tomography Scans for Pseudomonas Keratitis

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

AI-Based Decision-Support System for Diagnosing Acanthamoeba Keratitis Using In Vivo Confocal Microscopy Images

Endoplasmic Reticulum Stress Disrupts Mitochondrial Bioenergetics, Dynamics and Causes Corneal Endothelial Cell Apoptosis

NF-κB c-Rel Is a Potential Therapeutic Target for Acute Corneal Transplant Rejection

Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults

Functional Changes of the Ocular Surface Sensory Nerves Due to Contact Lens Use in Young Symptomatic and Asymptomatic Users

Diabetes-Associated Hyperglycemia Causes Rapid-Onset Ocular Surface Damage

Corneal Vascularization Associated With a Novel PDGFRB Variant

Impact of Single Constant Optimization on the Precision of IOL Power Calculation

A Novel Riboflavin Formulation for Corneal Delivery Without Damaging Epithelial Cells

Monitoring the Progression of Clinically Suspected Microbial Keratitis Using Convolutional Neural Networks

Interleukin-11 Suppresses Ocular Surface Inflammation and Accelerates Wound Healing

Establishing a Mouse Model of Chlorpromazine-Induced Corneal Trigeminal Denervation

Characterization of the Limbal Epithelial Stem Cell Niche

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis

Molecular and Phenotypic Characterization of Ocular Methicillin-Resistant Staphylococcus epidermidis Isolates in Taiwan

Adipose Mesenchymal Stem Cell-Derived Exosomes Promote the Regeneration of Corneal Endothelium Through Ameliorating Senescence

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